Laboratorija za molekularnu biomedicinu

Laboratorija za molekularnu biomedicinu ima reputaciju postignutu istraživačkim rezultatima i ekpertizom u dijagnostici različitih retkih bolesti u Srbiji i na Balkanu. Napori LMB su usmereni ka istraživanjima molekularne osnove zdravlja i bolesti i translacionoj biomedicini sa ciljem da se u zdravstvenom sistemu primeni personalizovana medicina zasnovana na ličnom genomu pacijenta.

Uspešna saradnja sa brojnim istaknutim centrima i vrhunskim naučnicima iz zemalja EU rezultirala je i zajedničkim radovima, te partnerstvom u značajnim projektima. U svojim istraživanjima, LMB uspešno sarađuje sa eminentnim zdravstvenim ustanovama u Srbiji i zemljama Balkana, a stečeno znanje se primenjuje za stalno unapređenje medicinske prakse uvođenjem molekularno genetičke dijagnoze genetičkih poremećaja i maligniteta. Za mnoga genetička testiranja, LMB je jedinstveno mesto na Balkanu. Tim LMB aktivno učestvuje u obrazovanju mladih kadrova u okviru Univerziteta u Beogradu, naročito u procesu izrade multidisciplinarnih doktorskih teza. Takođe, popularizacija i promocija molekularne genetike, genomike i biomedicine na svim nivoima je stalna aktivnost istraživača Laboratorije za molekularnu biomedicinu. 

• Program rada IMGGI za 2022. godinu
  Ministarstvo prosvete, nauke i tehnološkog razvoja Republike Srbije, 451-03-68/2022-14/200042, 2022
  Rukovodilac: Dr Jelena Begović, IMGGI
  Učesnici iz IMGGI: svi zaposleni istraživači
• European Network for Innovative Diagnosis and Treatment of Chronic Neutropenias (EuNet-INNOCHRON)
  COST akcija CA18233, 2019-2023
  Učesnici iz IMGGI: Dr Sonja Pavlović, dr Anita Skakić, dr Kristel Klaassen, dr Vladimir Gašić, dr Marina Anđelković
• ADHEsion GPCR Network: Research and Implementation Set the path for future Exploration (Adher'n Rise) 
  COST akcija CA18240, 2019-2023
  Učesnici iz IMGGI: Dr Biljana Stanković, dr Nikola Kotur

• Science on the move - from lab to streets & school (ScienceSCool)
  Evropska komisija, 101061631, 2022-2023
  Rukovodilac: Dr Biljana Šljukić Paunković, Fakultet fizičku hemiju, Univerzitet u Beogradu
  Učesnik iz IMGGI: Dr Milena Ugrin

RUKOVODILAC:

• Sonja Pavlović - Naučni savetnik

NAUČNI SAVETNICI:

• Maja Stojiljković
• Branka Zukić
• Nataša Tošić

VIŠI NAUČNI SARADNICI:

• Milena Ugrin
• Vesna Spasovski
• Teodora Karan-Đurašević
• Biljana Stanković
• Nikola Kotur
• Kristel Klassen Ljubičić

NAUČNI SARADNICI:

• Sanja Srzentić Dražilov
• Jelena Perić
• Tatjana Kostić
• Marina Anđelković
• Irena Marjanović
• Anita Skakić
• Vladimir Gašić
• Jovana Komazec
• Bojan Ristivojević

ISTRAŽIVAČI SARADNICI:

• Đorđe Pavlović

ISTRAŽIVAČI PRIPRAVNICI:

• Nina Stevanović
• Marina Jelovac

OSTALI:

• Marina Parezanović

• Pharmacogenomic and Pharmacotranscriptomic Profiling of Childhood Acute Lymphoblastic Leukemia: Paving the Way to Personalized Treatment
  Pavlovic S, Kotur N, Stankovic B, Zukic B, Gasic V, Dokmanovic L
  Genes (Basel) 2019;10(3):E191
• CRISPR/Cas9 genome editing of SLC37A4 gene elucidates the role of molecular markers of endoplasmic reticulum stress and apoptosis in renal involvement in glycogen storage disease type Ib
  Skakic A, Andjelkovic M, Tosic N, Klaassen K, Djordjevic M, Pavlovic S, Stojiljkovic M
  Gene 2019;703:17-25
• Genomic profiling supports the diagnosis of primary ciliary dyskinesia and reveals novel candidate genes and genetic variants
  Andjelkovic M, Minic P, Vreca M, Stojiljkovic M, Skakic A, Sovtic A, Rodic M, Skodric-Trifunovic V, Maric N, Visekruna J, Spasovski V, Pavlovic S
  PLoS One 2018;13(10):e0205422
• Intra-articular injection of autologous adipose-derived mesenchymal stem cells in the treatment of knee osteoarthritis
  Spasovski D, Spasovski V, Baščarević Z, Stojiljković M, Vreća M, Anđelković M, Pavlović S
  J Gene Med 2018;20(1):e3002
• Expanded national database collection and data coverage in the FINDbase worldwide database for clinically relevant genomic variation allele frequencies
  Viennas E, Komianou A, Mizzi C, Stojiljkovic M, Mitropoulou C, Muilu J, Vihinen M, Grypioti P, Papadaki S, Pavlidis C, Zukic B, Katsila T, van der Spek PJ, Pavlovic S, Tzimas G, Patrinos GP
  Nucleic Acids Res 2017;45(D1):D846-D853
• Parallel targeted next generation sequencing of childhood and adult acute myeloid leukemia patients reveals uniform genomic profile of the disease
  Marjanovic I, Kostic J, Stanic B, Pejanovic N, Lucic B, Karan-Djurasevic T, Janic D, Dokmanovic L, Jankovic S, Vukovic NS, Tomin D, Perisic O, Rakocevic G, Popovic M, Pavlovic S, Tosic N
  Tumour Biol 2016;37(10):13391-13401
• A European Spectrum of Pharmacogenomic Biomarkers: Implications for Clinical Pharmacogenomics
  Mizzi C, Dalabira E, Kumuthini J, Dzimiri N, Balogh I, Başak N, Böhm R, Borg J, Borgiani P, Bozina N, Bruckmueller H, Burzynska B, Carracedo A, Cascorbi I, Deltas C, Dolzan V, Fenech A, Grech G, Kasiulevicius V, Kádaši Ľ, Kučinskas V, Khusnutdinova E, Loukas YL, Macek M Jr, Makukh H, Mathijssen R, Mitropoulos K, Mitropoulou C, Novelli G, Papantoni I, Pavlovic S, Saglio G, Setric J, Stojiljkovic M, Stubbs AP, Squassina A, Torres M, Turnovec M, van Schaik RH, Voskarides K, Wakil SM, Werk A, Del Zompo M, Zukic B, Katsila T, Lee MT, Motsinger-Rief A, Mc Leod HL, van der Spek PJ, Patrinos GP
  PLoS One 2016;11(9):e0162866
• Gene Mutation Profiles in Primary Diffuse Large B Cell Lymphoma of Central Nervous System: Next Generation Sequencing Analyses
  Todorovic Balint M, Jelicic J, Mihaljevic B, Kostic J, Stanic B, Balint B, Pejanovic N, Lucic B, Tosic N, Marjanovic I, Stojiljkovic M, Karan-Djurasevic T, Perisic O, Rakocevic G, Popovic M, Raicevic S, Bila J, Antic D, Andjelic B, Pavlovic S
  Int J Mol Sci 2016;17(5):E683
• Maritime route of colonization of Europe
  Paschou P, Drineas P, Yannaki E, Razou A, Kanaki K, Tsetsos F, Padmanabhuni SS, Michalodimitrakis M, Renda MC, Pavlovic S, Anagnostopoulos A, Stamatoyannopoulos JA, Kidd KK, Stamatoyannopoulos G.
  Proc Natl Acad Sci U S A 2014;111(25):9211-9216
• Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach
  Giardine B, Borg J, Higgs D, Peterson K, Philipsen S, Maglott D, Singleton B, Anstee D, Basak AN, Clark B, Costa F, Faustino P, Fedosyuk H, Felice A, Francina A, Galanello R, Gallivan M, Georgitsi M, Gibbons R, Giordano P, Harteveld C, Hoyer J, Jarvis M, Joly P, Kanavakis E, Kollia P, Menzel S, Miller W, Moradkhani K, Old J, Papachatzopoulou A, Papadakis M, Papadopoulos P, Pavlovic S, Perseu L, Radmilovic M, Riemer C, Satta S, Schrijver I, Stojiljkovic M, Thein SL, Traeger-Synodinos J, Tully R, Wada T, Waye J, Wiemann C, Zukic B, Chui D, Wajcman H, Hardison R, Patrinos P
  Nat Genet. 2011;43(4):295-301

Adresa sedišta / Poštanska adresa:
Vojvode Stepe 444a,
11042 Beograd 152, Srbija

Tel: +381 11 3976445
Faks: +381 11 3975808

zmzg@imgge.bg.ac.rs