Sonja Pavlović

Full Research Professor

Institute of Molecular Genetics and Genetic Engineering (IMGGE),
University of Belgrade

Vojvode Stepe 444a, 11042 Belgrade 152, Serbia
Mobile:  +381 65 397 64 45                          
Phone:  +381 11 397 64 45
Fax:      +381 11 397 58 08


2001 - Full Research Professor (Principal Reseach Fellow) Laboratory for Molecular Hematology (LMH) and Laboratory for Molecular Biomedicine (LMB), IMGGE
1996 - M.Sc. in Molecular Genetics and Genetic Engineering, FB, UB
1992 - B.Sc. in Molecular Biology and Physiology, FB, University of Belgrade


2011 - Principal Reseach Fellow Laboratory for Molecular Hematology (LMH) and Laboratory for Molecular Biomedicine (LMB), IMGGE
2007 - 2011 - Senior Research AssociateLMH, IMGGE
2002 - 2007 - Research Associate LMH, IMGGE
1996 - 2002 - Research Assistant LMH, IMGGE
1993 - 1996 - Research Trainee, LMH, IMGGE


2015 - Head of  LMB, IMGGE 
2013 - 2015 -
Principal Investigator LMB, IMGGE
2001- 2013 - Head of  LMH, IMGGE
2000 - Lecturer on Faculty of Biology, UB
2009 - Leader of Science Promotion and Popularization Program “Short Course of DNAlogy” 
2011 - Serbian National Coordinator of PGENI (Pharmacogenetics for Every Nation Initiative)
2011 - Member of the Council of the Institutes University of Belgrade
2012 - Member of the Academic Council of Medical Sciencies University of Belgrade
2005 - Guest scientist. Centro Ricerca M. Tettamanti, Universita di Milano-Biccoca, H. San Gerardo, Monza, Italy
1999 - Guest scientist. Istituto di Clinica e Biologià dell’Età Evolutiva Università degli Studi, Cagliari, Italy
1993 - 2001 - Staff member, LMH, IMGGE
1983 - 1994 - Piano teacher in the Music School


  1. European Network for Innovative Diagnosis and Treatment of Chronic Neutropenias  (EuNet-INNOCHRON) - COST action CA18233, European Commission 2019-2023.
  2. Pharmacogenomic markers in immunosuppressive and immunomodulatory therapy: from validated markers to genotyping kits and clinical algorithms (bilateral project between Republic of Serbia and Republic of Slovenia 451-03-3095/2014-09/45), 2014- 2015.
  3. Strengthening the Research Potential of IMGGE through Reinforcement of Biomedical Science of Rare Diseases in Serbia – en route for innovation (SERBORDISinn), EU FP7-REGPOT-2012-2013-1, European Commission, 2013-2016. Principal Investigator
  4. „RD-CONNECT“ (EU-FP7), European Commission, 2012-2018.
  5. Rare diseases: Molecular Pathophysiology, Diagnostic and Therapeutic Modalities and Social, Ethical and Legal Aspects (integrative and interdisciplinary research project, No. III 41004), Ministry of Science and Technological Development, Republic of Serbia, 2011-2019. Principal Investigator
  6. Researchers’Night Fever „RENIFEVER“ (CSA-SA, FP7-PEOPLE-2011-NIGHT- 287432), European Commission, 2011. Principal Investigator
  7. Short course of DNAlogy (science popularisation project), Center for Popularization of Science, Republic of Serbia, 2009- 2011. Principal Investigator
  8. Health improvement in Serbia trough reinforcement of biomedical science and technology “HISERBS” (SSA, FP6-INCO-026357), European Commission, 2006-2009.
  9. European LeukemiaNet -“Strengthen and develop scientific and technological excellence in research and therapy of leukemia (CML, AML, ALL, CLL, MDS, CMPD) by integration of the leading national leukemia networks and their interdisciplinary partner groups in Europe” (FP6, LSHC-CT-2004-503216), European Commission, 2004-2015.


Molecular genetics of rare diseases, thalassemia (regulation of transcription of beta-globin genes, modifier genes), hematological malignancies (molecular markers of childhood and adult acute and chronic myeloid and lymphoid leukemias, lymphomas and multiple myelomas), metabolic diseases (phenylketonuria, glycogenosis,  organic acidurias), congenital adrenal hyperplasia, molecular genetics of inflammatory bowel diseases (Crohn’s disease, ulcerative colitis, celiac disease), pulmonary diseases (tuberculosis, idiopathic pulmonary fibrosis, hereditary pulmonary hypertension, sarcoidosis, primary ciliary dyskinesia), rheumatological diseases (systemic sclerosis, myositis, rheumatoid arthritis), orthopedic diseases, inflammation, autoimmunity, genotype-phenotype correlation, population genetics, stem cell and gene therapy and pharmacogenomics.

Research activities also resulted in the introduction of the molecular diagnosis of rare diseases in Serbia, as well as improved therapeutic protocols for several diseases.


Teaching activities of Sonja Pavlovic include seminars and courses at the Faculty of Biology, Faculty of Medicine and Faculty of Pharmacy, University of Belgrade. Sonja Pavlovic has been a supervisor of more than 40 master and doctoral theses.


Sonja Pavlovic has published more than 180 articles in peer reviewed journals and books, cited for more than 2000 times.

  1. Klaassen, K., Stankovic, B., Zukic, B., Kotur, N., Gasic, V., Pavlovic, S., Stojiljkovic, M. Functional prediction and comparative population analysis of variants in genes for proteases and innate immunity related to SARS-CoV-2 infection. Infect Genet Evol. 2020 Aug 7;84:104498. doi: 10.1016/j.meegid.2020.104498.
  1. Stankovic B, Kotur N, Gasic V, Klaassen K, Ristivojevic B, Stojiljkovic M, Pavlovic S, Zukic B. Pharmacogenomics landscape of COVID-19 therapy response in Serbian population and comparison with worldwide populations. Journal of Medical Biochemistry (2020);39(4),:488-499. Doi: 10.5114/aoms.2020.96537.
  1. Pavlovic S, Kotur N, Stankovic B, Zukic B, Gasic V, Dokmanovic L. Pharmacogenomic and Pharmacotranscriptomic Profiling of Childhood Acute Lymphoblastic Leukemia: Paving the Way to Personalized Treatment. Genes (Basel). 2019 Mar 1;10(3). pii: E191. doi: 10.3390/genes10030191.
  1. Komazec J, Zdravkovic V, Sajic S, Jesic M, Andjelkovic M, Pavlovic S, Ugrin M. The importance of combined NGS and MLPA genetic tests for differential diagnosis of maturity onset diabetes of the young. Endokrynol Pol. 2019;70(1):28-36. doi: 10.5603/EP.a2018.0064. Epub 2018 Sep 27.
  1. Andjelkovic M, Minic P, Vreca M, Stojiljkovic M, Skakic A, Sovtic A, Rodic M, Skodric-Trifunovic V, Maric N, Visekruna J, Spasovski V, Pavlovic S. Genomic profiling supports the diagnosis of primary ciliary dyskinesia and reveals novel candidate genes and genetic variants. PLoS One. ; 13(10):e0205422; doi: 10.1371/journal.pone.0205422.
  1. Spasovski D, Spasovski V, Bascarevic Z, Stojiljkovic M, Vreca M, Andjelkovic M, Pavlovic S. Intra-articular Injection of Autologous Adipose Derived Mesenchymal Stem Cells in Treatment of Knee Osteoarthritis. The Journal of Gene Medicine, 2018; 20(1).
  1. Dragasevic S, Stankovic B, Milosavljevic T, Sokic-Milutinovic A, Lukic S, Alempijevic T, Zukic B, Kotur N, Nikcevic G, Pavlovic S, Popovic D. Genetic and environmental factors significant for the presentation and development of inflammatory bowel disease. Eur J Gastroenterol Hepatol. 2017 Aug;29(8):909-915.
  1. Skakic A, Djordjevic M, Sarajlija A, Klaassen K, Tosic N, Kecman B, Ugrin M, Spasovski V, Pavlovic S, Stojiljkovic M. Genetic characterization of GSD I in Serbian population revealed unexpectedly high incidence of GSD Ib and three novel SLC37A4 variants. Clin Genet. 2017 Jul 7. doi: 10.1111/cge.13093.
  1. Viennas E, Komianou A, Mizzi C, Stojiljkovic M, Mitropoulou C, Muilu J, Vihinen M, Grypioti P, Papadaki S, Pavlidis C, Zukic B, Katsila T, van der Spek PJ, Pavlovic S, Tzimas G, Patrinos GP. Expanded national database collection and data coverage in the FINDbase worldwide database for clinically relevant genomic variation allele frequencies. Nucleic Acids Res. 2017 Jan 4;45(D1):D846-D853
  1. Mizzi C, Dalabira E, Kumuthini J, Dzimiri N, Balogh I, Başak N, Böhm R, Borg J, Borgiani P, Bozina N, Bruckmueller H, Burzynska B, Carracedo A, Cascorbi I, Deltas C, Dolzan V, Fenech A, Grech G, Kasiulevicius V, Kádaši Ľ, Kučinskas V, Khusnutdinova E, Loukas YL, Macek M Jr, Makukh H, Mathijssen R, Mitropoulos K, Mitropoulou C, Novelli G, Papantoni I, Pavlovic S, Saglio G, Setric J, Stojiljkovic M, Stubbs AP, Squassina A, Torres M, Turnovec M, van Schaik RH, Voskarides K, Wakil SM, Werk A, Del Zompo M, Zukic B, Katsila T, Lee MT, Motsinger-Rief A, Mc Leod HL, van der Spek PJ, Patrinos GP. A European spectrum of pharmacogenomic biomarkers: Implications for clinical pharmacogenomics. PLoS One. 2016 Sep 16;11(9):e0162866. doi: 10.1371/journal.pone.0162866 .
  1. Stojiljkovic M, Klaassen K, Djordjevic M, Sarajlija A, Brasil S, Kecman B, Grkovic S, Kostic J, Rodriguez-Pombo P, Desviat LR, Pavlovic S, Perez B. Molecular and phenotypic characteristics of seven novel mutations causing branched-chain organic acidurias. Clin Genet. 2016 Sep;90(3):252-7.
  1. Todorovic Balint M, Jelicic J, Mihaljevic B, Kostic J, Stanic B, Balint B, Pejanovic N, Lucic B, Tosic N, Marjanovic I, Stojiljkovic M, Karan-Djurasevic T, Perisic O, Rakocevic G, Popovic M, Raicevic S, Bila J, Antic D, Andjelic B, Pavlovic S. Gene Mutation Profiles in Primary Diffuse Large B Cell Lymphoma of Central Nervous System: Next Generation Sequencing Analyses. Int J Mol Sci. 2016 May 6;17(5). pii: E683. doi: 10.3390/ijms17050683.
  1. Milacic I, Barac M, Milenkovic T, Ugrin M, Klaassen K, Skakic A, Jesic M, Joksic I, Mitrovic K, Todorovic S, Vujovic S, Pavlovic S, Stojiljkovic M. Molecular genetic study of congenital adrenal hyperplasia in Serbia: novel p.Leu129Pro and p.Ser165Pro CYP21A2 gene mutations. J Endocrinol Invest. 2015; 38(11): 1199-210.
  1. Stankovic B, Dragasevic S, Popovic D, Zukic B, Kotur N, Sokic-Milutinovic A, Alempijevic T, Lukic S, Milosavljevic T, Nikcevic G, Pavlovic S. Variations in inflammatory genes as molecular markers for prediction of inflammatory bowel disease occurrence. J Dig Dis. 2015; 16(12):723-33.
  1. Pavlovic S, Ugrin M, Stojiljkovic M. Novel Therapy Approaches in Beta Thalassemia Syndromes — A Role of Genetic Modifiers In: Hemoglobin Disorders (ed: Anjana Munshi), pp. 75-94 (2015). InTech, Rijeka, Croatia. 
  1. Srzentić S, Nikčević G, Spasovski D, Baščarević Z, Živković Z, Terzic-Šupić Z, Matanović D, Djordjević V, Pavlović S, Spasovski V. Predictive genetic markers of coagulation, inflammation and apoptosis in Perthes disease - Serbian experience. European Journal of Pediatrics. 2015; 174(8): 1085-92.
  1. Paschou P, Drineas P, Yannaki E, Razou A, Kanaki K, Tsetsos F, Padmanabhuni SS, Michalodimitrakis M, Renda MC, Pavlovic S, Anagnostopoulos A, Stamatoyannopoulos JA, Kidd KK, Stamatoyannopoulos G. Maritime route of colonization of Europe. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9211-6
  1. Rodic P, Pavlovic S, Kostic T, Suvajdzic Vukovic N, Djordjevic M, Sumarac Z, Dajak M, Bonaci Nikolic B, Janic D. Gammopathy and B lymphocyte clonality in patients with Gaucher type I disease. Blood Cells Mol Dis. 2013 50: 222-225.
  1. Jančić I, Arsenović-Ranin N, Sefik-Bukilica M, Zivojinović S, Damjanov N, Spasovski V, Srzentić S, Stanković B, Pavlović S. -174G/C interleukin-6 gene promoter polymorphism predicts therapeutic response to etanercept in rheumatoid arthritis. Rheumatol Int. 2013 Jun;33(6):1481-6.
  1. Giardine B, Borg J, Higgs D, Peterson K, Philipsen S, Maglott D, Singleton B, Anstee D, Basak AN, Clark B, Costa F, Faustino P, Fedosyuk H, Felice A, Francina A, Galanello R, Gallivan M, Georgitsi M, Gibbons R, Giordano P, Harteveld C, Hoyer J, Jarvis M, Joly P, Kanavakis E, Kollia P, Menzel S, Miller W, Moradkhani K, Old J, Papachatzopoulou A, Papadakis M, Papadopoulos P, Pavlovic S, Perseu L, Radmilovic M, Riemer C, Satta S, Schrijver I, Stojiljkovic M, Thein SL, Traeger-Synodinos J, Tully R, Wada T, Waye J, Wiemann C, Zukic B, Chui D, Wajcman H, Hardison R, Patrinos P. Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach. Nat Genet 2011: 43(4): 295-301.
  1. Pavlovic S. TPMT gene polymorphisms: on the doorstep of personalized medicine. Indian J Med Res. 2009 May;129(5):478-80.
  1. Stojiljkovic M, Jovanovic J, Djordjevic M, Grkovic S, Cvorkov Drazic M, Petrucev B, Tosic N, Karan Djurasevic T, Stojanov L, Pavlovic S. Molecular and phenotypic characteristics of patients with phenylketonuria in Serbia and Montenegro. Clin Genet. 2006 Aug;70(2):151-5.
  1. Pavlovic S, Urosevic J, Poznanic J, Perisic Lj, Petrucev B, Tosic N, Krivokapic-Dokmanovic L, Janic D, Cvorkov-Drazic M, Bunjevacki G. (2005) Molecular basis and origin of thalassemia syndromes in Serbia. Acta Haematologica 113, 175-180.

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