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INSTITUTE OF MOLECULAR GENETICS
AND GENETIC ENGINEERING
University of Belgrade

Master Theses

2023.

Aleksa Timotijevic
Frequency comparison of variants in genes DIO1 and DIO2 associated with response to thyroxine in Serbian and European populations and bioinformatic prediction of their effect on transription factor binding

Darko Cucin
Effects of myeloid derived suppressor cells therapy on gut microbiota diversity in C57BL/6 mouse model of experimental autoimmune encephalomyelitis and the role of microbiota derived metabolites in a model of gut inflammation in vitro

Isidora Curic
Association of variants in TPMT, NUDT15, ITPA, MTHFR and SLCO1B1 genes with response to mercaptopurine and methotrexate therapy in Croatian children with acute lymphoblastic leukemia

Lana Denic
The effect of Lactiplantibacillus plantarum BGAN8 on HT-29 cells gene expression

Milica Kovacevic
Optimization of antibacterial compounds production in isolate Brevivacillus sp. KK13

Milica Radovanovic
The role of efflux pumps AdeABC, AdeFGH, and AdeIJK in tigecycline resistance in clinical isolates of Acinetobacter baumannii

Nikola Jocic
Investigation of the role of the glucose-6-phosphate translocase in the activation of autophagy and glycogen-selective autophagy in GSD Ib patients

Nikola Plackic
Toxicological profiling and efficacy evaluation of clinical antifungal drugs in vivo in the zebrafish (Danio rerio) models

Petar Djurdjic
Optimization of Brevibacillus laterosporus BGSP11 sporulation process on laboratory fermenter BioFlo C30

Sofija Ignjatovic
Analysis of PHF19-207 transcript expression in colon carcinoma cell lines

Teodora Barisic
Association between variants in Fatty Acid Desaturase 1 gene (FADS1) and COVID-19 severity

Tijana Pesovic
Biological degradation of recycled jute used as adsorbens for crude oil

Vera Pavic
The generation of knockout of the gene ZFP161 in human U937 monocytes by using CRISPR method

2022. 

Bojan Ilic
The effects of human alpha-1 antitrypsin on tail fin regeneration process in zebrafish

Dunja Pavlovic
Transcriptional profiling of PRKAR1B gene in colon cancer cell lines

Helena Katanic
Modulatory effects of Lactobacillus delbrueckii subsp. lactis BGAZEJ1-49 during enteropathogenic Salmonella enteritidis 654/7E infection in vitro

Lena Pantelic
Biotechnological production and application of pyocyanin and 1-hydroxyphenazine

Luka Bojic
Effect of UVB irradiation on SOX2 and SOX9 gene expression in a permanent cell line derived from human keratinocytes

Mirjana Babic
The antioxidative effect of heat killed lactic acid bacteria on the level of expression of the AHR and NRF2 genes in bronchial epithelial cells stimulated by cigarette smoke

Nikoleta Milanovic
Variants in the 3' end of the prothrombin gene in patients with repeated thrombosis of unknown cause

Nina Dobric
Mutation profile analysis in signet ring cell carcinoma

Tijana Ganic
Biocatalytic potential of selected bacterial isolates for polyurethan degradation

2021.

Ana Pantelic
Optimisation of protocol for production of late embryogenesis abound protein (RsLEA_30) in resurrection plant Ramonda serbica, in bacteria Escherichia coli by recombinant DNA technology

Andjela Djokic
Characterization and biological activity of MhqO dioxygenase from isolate Bacillus paralicheniformis ZP1

Dusan Stevanovic
Antimicrobial potential of natural isolate of Enterococcus faecium BGZLM1-5

Hristina Mitrovic
Analysis of the role of human ZF5 transcription factor in the regulation of MMP9 gen expression

Ivana Mladenovic
Impact of water deficit on the concentration of photosynthetic pigments and expression of GLUTR and PSBI genes in maize (Zea mays)

Jovana Curcic
Identification and characterization of lactonases from Stenotrophomonas maltophilia strains

Kosta Stosic
Selection and identification of biosurfactant producing bacteria isolated from plastic contaminated soils

Marina Jelovac
Association study of clinical presentation of COVID-19 with variants in genes related to the level and bioavailability of vitamin D

Marina Parezanovic
Molecular diagnosis of Fabry disease in patients with chronic renal failure of unknown etiology

Marko Djokic
Tolerance increase of indigenous bacteria from cosmetic industry wastewater to sodium dodecyl sulfate using adaptive laboratory evolution

Milena Zivanovic
Analysis of SMAD4 gene transcripts in HCEC-1CT cell line during stress response

Mina Milovanovic
Generation of transgenic zebrafish reporter line Tg(ankrd1b:mScarlet)

Miona Corovic
Association of nutrigenetic markers of zinc and selenium with the severity of the clinical picture of COVID-19

Nemanja Markovic
Optimisation of protocol for efficient production of late embryogenesis abound protein (AtLEA_25) in resurrection plant Arabidopsis thaliana by recombinant DNA technology

Stefan Jakovljevic
Effect of probiotic strain Lactobacillus curvatus BGMK2-41 to immune response mediated by p38 MAPK signal pathway in model of infection of nematode Caenorhabditis elegans

2020.

Anja Stankovic
Identification of silver complexes effective against Cryptococcus neoformans and Cryptococcus gattii infections

Djordje Pavlovic
Analysis of expression of the long non-coding RNA GAS5 in adult acute myeloid leukemia

Djurdja Madzarac
Heterologous expression of lipase from Streptomyces sp. BV129 with the potential application in the treatment of Pseudomonas aeruginosa biofilm

Emilija Zivkovic
The effect of alpha-1 antitrypsin on 5-Fluorouracil treatment in colorectal cancer cells

Goran Milosevic
Influence of variants in genes important for farmacokinetics of 6-mercaptopurine on acute lymphoblastic leukemia treatment in children

Ivana Lalic
Analysis of APC gene exon 15 in patients with colorectal carcinoma

Jelena Jordovic
Impact of sustained virological response on the outcome and prognosis in patients with severe fibrosis and cirrhosis caused by chronic hepatitis C infection

Mihailo Stjepanovic
Significance of serum vitamin 25(OH)D determination and CYP2R1, CYP27B1, DBP and VDR polymorphisms in sarcoidosis patients

Milena Stevanovic
Identification of sta cluster in Streptomyces sp. BV410 isolate and its expression in the presence of different butenolides

Milica Velimirovic
Analysis of the effect of selected miRNAs on the expression of SOXB genes in cell lines derived from glioblastoma

Natalija Azanjac
Isolation and molecular characterization of blm mutant suppressors under replication stress in Ustilago maydis

Nina Stevanovic
Molecular characterization of novel genetic variants in patients with primary ciliary dyskinesia

Sanja Dragasevic
Intestinal gene expression of IL17A, IL17F, IL23A and TLR9 in inflammatory bowel diseases

Teodora Malesevic
Transcriptional analysis and functional characterization of two-component system MqiSR regulon in Pseudomonas putida WCS358

Vukasin Jankovic
Cotinus coggyria as a source of bacterial isolates with laccase activity

2019.

Brana Pantelic
Characterization of a cutinase from strain Streptomyces sp. BV286

Danijela Blagojevic
Optimization of nanocellulose production from Komagataeibacter medellinensis ID13488 strain

Filip Duzanic
Analysis of stress induced by cobalt chloride on maintainance of pluripotency and induction of neuronal differentiation of human pluripotent embryonal carcinoma cells

Ivana Galic
Genome mining of industrially important enzymes in Streptomyces sp. NP10

Jelena Micevic
Establishment of the Staphylococcus aureus ATCC43300-zebrafish (Danio rerio) infection model and its usage for novel antimicrobial drugs discovery

Jelena Milovanovic
The effect of ethanolic extract of defensive secretion of Megaphyllum unilineatum (C. L. Koch, 1838) (Diplopoda: Julida) on early development of zebrafish (Danio rerio (F. Hamilton, 1822)) and viability of A549 human lung adenocarcinoma cell line

Lana Dzodanovic
Identification of informative regions of mitochondrial and chloroplast maize (Zea mays) genomes important for genotyping the origin of elite maize hybrids in Serbia

Lazar Gardijan
Expression of gramicidin A, non-ribosomally synthesized antimicrobial peptide in Escherichia coli expression systems

Mirjana Latincic
Interactions of small bioactive molecules of different origin with DNA

Pavle Janic
Comparative analysis of drought-induced gene expression change in maize leaves (Zea mays)

Sandra Predic
Determination and comparison of cytokine expression profiles of IL-6 and TNF-α in inflamed and healthy tissue of patients with ulcerative colitis

Zivan Stojanovic
Optimization of lactolisterin BU production in Lactococcus lactis subsp. lactis BGBU1-4

2018.

Vanda Balint
The role of SOX2 and SOX9 genes in reactivation of human NT2-astrocytes

Neda Dragisic
The effect of stress induced by short-term glucose deprivation on human pluripotent embryonal carcinoma stem properties

Milos Dzebric
The analysis of the role of miR-219 in induction of neural differentiation of human pluripotent NT2/D1 cells

Gorana Jendrisek
Effect of montelukast on inflammation in cell line BEAS2B

Danica Jevtic
The analysis of effects of SOX18 gene expression modulation on the features of U251 glioblastoma cells

Jovana Kaljevic
Identification of a novel intI1 gene variant in mobile integrons class I

Mina Ledjenovic
Isolation of Lactobacillus strains with tannase and gallate decarboxylase activity from silage

Emilija Milosevic
Detection of Ankrd1a protein in zebrafish (Danio rerio) heart after cryoinjury

Sofija Nesic
The role of silicon in alleviation of iron deficiency in barley (Hordeum vulgare)

Ivana Srbljak
Analysis of variants c.454-397T>C and c.454-351A>G in estrogen receptor alpha gene: correlation with myocardial infarction and carotid artery stenosis

Milena Stanojevic
Analysis of SMAD4 expression profile in lung cell lines

Boris Stojilkovic
Functional characterization of mobile integrons class I IntI1S protein

Jovanka Vladejic
Effects of synthetic quinones on seed germination and seedling growth of maize (Zea mays L.)

Marija Vukcevic
Isolation of Ustilago maydis desiccation-sensitive mutants

 

2017.

Ali Musbah Mohamed Aldrhoubi
Bacterial diversity in sediments of selected western Balkans glacial lakes

Marko Bicin
Analysis of association between FokI, BsmI, ApaI and TaqI genetic variants in vitamin D receptor gene and occurrence and presentation of Crohn's disease 

Aleksa Cepic
Correlation of gut microbiota and short-chain fatty acids from feces in experimental autoimmune encephalomyelitis

Sofija Dunjic
Prothrombin expression in cancer-derived cell lines

Stefana Djukanovic
Antibacterial and antibiofilm activity of selected hop (Humulus lupulus) and drowsiness extracts (Helichrysum italicum)

Jelena Jeremic
Study of the effects of N-benzyl-substituted derivatives of 4-aminoquinoline on intercellular communication and the virulence of Serratia marcescens and Pseudomonas aeruginosa

Sofija Jovanovic
Isolation and molecular characterization of bacteriocin producing strains of Brevibacillus laterosporus

Marko Kozlina
Analysis of association between FokI, BsmI, ApaI and TaqI genetic variants in vitamin D receptor gene with occurrence and presentation of Crohn’s disease

Branislav Lilic
Molecular mechanisms of fluoroquinolone resistance in Achromobacter sp. clinical isolates

Pavle Marinkovic
Characterization of the lactolisterin-BU operon from strain Lactococcus lactis subsp. lactis BGBU1-4

Tijana Milicevic
Molecular mechanisms of trimethoprim and sulfomethaxozole resistance in Achromobacter sp. clinical isolates

Kristina Popic
Characterization of chicken (Gallus gallus) ANKRD2 gene expression

Nemanja Stamenkovic
Expression of ldb3а gene in mechanical stress response of zebrafish (Danio rerio) skeletal muscle

Anja Todorov
Characterization of the lactolisterin-BU operon from strain Lactococcus lactis subsp. lactis BGBU1-4

 

2016.

Ana Arsenijevic
The effects of retinoic acid on proliferation, cell cycle and migration of MCF-7 breast carcinoma cells

Emilija Brdaric
The role of lactic acid bacteria egzopolysaccharides in protection of Caco-2 cells from toxic effect of cadmium

Dunja Djukic
Influence of DNA isolation methods on CaMV 35S promoter detection by the PCR method in food samples of plant origin

Tamara Jovanovic
Analysis of the role of prothrombin in colon cancer

Ana Kojic
Characterization of Ankrd1 protein in glioblastoma cell lines U87-MG and LN229

Tamara Kovacevic
The effects of mTOR kinase inhibitors on early embryonic development of zebrafish (Danio rerio)

Ivana Nikolic
Expression analysis of the gene encoding DSS1 protein in arabidopsis under oxidative stress

Vladislava Stokic Trtica
Development of system for genetic manipulations with Acinetobacter baumannii clinical isolates

Danijela Vucicevic
The analysis of the VKORC1 gene coding region in patients under acenocoumarol therapy

 

2015.

Ivana Aleksic
The role of tripyrolin pigments from streptomycetes in bacterial communication

Katarina Cukovic
Protective role of silicon in barley (Hordeum vulgare L) under iron deficiency stress

Ana Dale
Biofilm formation of Burkholderia cepacia complex isolates from cystic fibrosis patients

Jovana Despotovic
The analysis of effects of SOX3 gene overexpression on the features of U87 and U251 glioblastoma cells

Aleksej Drino
Correlation between the mutational status of the ATM and TP53 gene and the mutational status of the genes involved in neoplastic transformation in primary central nervous system lymphoma

Marija Dragojevic
The influence of the FII c.1824C>T variant on nucleus and cytoplasm prothrombin mRNA level in stably transfected cos-7 cell line

Sanja Djokic
Expression analysis of Medicago truncatula putative molybdenum transporter, MtrMOT1

Marija Gredic
Construction and functional analysis of human SOX14 mutant forms

Magdalena Jerkovic
Phylogenetic analysis of thermophilic bacteria isolated from thermal springs

Jelena Lazic
The effect of lysine on the production of γ-nitroaldehyde using reaction of Michael's addition: a comparative study of an organocatalytic and biocatalytic approach

Aleksandar M. Markovic
The influence of biologically active compounds on inter-bacterial communication

Milka Malesevic
Molecular characterization of Achromobacter xylosoxidans isolates from pediatric patients

Jelena Spasic
Optimization of the beta-nitrostyrene biotransformation process using recombinant 4-oxalocrotonate tautomerase

 

2014.

Marina Andjelkovic
Influence of NRAMP1 and VDR gene variants on altered function of macrophages in tuberculosis patients

Danica Bajic
Interaction of WNT/β-catenin signaling and SOXB1 genes in human NT2/D1 cells

Snezana Jovicic
Analysis of BRAF and KRAS mutations in thyroid tumor tissue

Ivana Kerkez
Genotyping and resistance to antibiotics of Stenotrophomonas maltophilia clinical isolates

Marija Mojicevic
Molecular identification and antimicrobial activity of streptomycete isolated from soil in the vicinity of Novi Sad

Sanja Pavlovic
Expression analysis of microRNA397 and 408 in the development and stress induced by the iron deficiency in cucumber

Marija Petric
Zebrafish (Danio rerio) as model system for autophagy research

Ivana Petrovic
Dynamic expression profile of SOXB1 proteins during in vitro neural differentiation of embryonic carcinoma stem cells

Nikola Popovic
Molecular mechanisms of resistance to antibiotics of enterococci isolated from environmental waters in Belgrade

Branislava Rankovic
Optimization of Hedgehog signaling modulation in HeLa cells

Svetlana Sokovic
Analysis of the gadB gene presence in lactic acid bacteria isolated from autochthonous cheeses from Balkan region

 

2013.

Marijana Aradjanski
The 3' end prothrombin gene variants in patients with idiopathic thrombophilia

Irena Jovanovic
Identification and characterization of the production of pigments in the soil isolate Streptomyces sp. NP60

Jelena Milic
Biochemical and genetic characterization of bacteriocin produced by natural isolate Lactococcus lactis BGBU1-4

Katarina Novovic
Molecular mechanisms of clinical isolate Acinetobacter baumannii IMD1865 resistance to antiobiotics

Ranko Radovic
Analysis of the influence of the c.454-397T>C polymorphism in the estrogen receptor alpha gene on the incidence of thrombosis in women with breast cancer

Mina Noshy Takawy
Impaired apoptosis as a cause of accumulation of malignant granulocytes in myeloproliferative neoplasms

Jelena Tosic
The effects of SOX2 gene overexpression on migration, proliferation and differentiation of embryonic carcinoma NT2/D1 cells

Milica Tosic
Neural differentiation of pluripotent NT2/D1 cells in conditions of constitutive SOX2 gene overexpression

 

2012.

Iva Lucic
Analysis of the influence of CYP2C9*2 i CYP2C9*3 polymorphisms on coumarin derivate based therapy

Haowa Madi
Co-dependance of bacteriocin synthesis and presence of plasmids in Lactococcus lactis subsp. lactis BGIS29 i BGJAV1 strains

Jelena Marjanovic
Effects of canonical WNT signaling modulation on SOX genes expression in human Ntera2/D1 cells

Jovana Mihajlovic
Optimization of undecylprodigiosin production in Streptomyces sp. NP4 strain

Marija Miljkovic
The role of polysaccharides in probiotic potential of strain Lactobacillus paracasei subsp. paracasei BGSJ2-8

Sara Selakovic
Analysis of the microbial communities of the Nadella River upstream and downstream of the pollution source

Diana Sevic
Effect of the petrochemical industry efflux on the composition of microbiological communities - metagenomic approach

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