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INSTITUTE OF MOLECULAR GENETICS
AND GENETIC ENGINEERING
University of Belgrade

PhD Theses

2023.

Emilija Brdaric
Characterization of the molecular basis of the protective effect of the exopolysaccharides from Lactobacilli in the DA rats model exposed to prolonged cadmium(II) exposure

Ivana Nikolic
Functional characterization of DSS1(I) and DSS1(V) in response to oxidative stress in Arabidopsis thaliana

Dusan Radojevic
Influence of intestinal microbiota composition on immunomodulatory properties and immunotherapeutic potential of dendritic cells and myeloid derived suppressor cells

Bojan Ristivojevic
Pharmacogenetic markers of response to therapy with thiopurine drugs, methotrexate and vincristine in children with acute lymphoblastic leukemia

2022.

Jelena Lazic
Structure optimisation of biopigment prodigiosin from Serratia marcescens ATCC 27117 and antimicrobial and anticancer properties of novel halogenated derivatives

Jelena Malesevic
Identification and characterization of cells factors involved in regeneration of the Ustilago maydis population after oxidative stress

Jovana Despotovic
The role of microRNAs involved in regulation of TGFB signaling pathway in metastatic colorectal cancer - functional analysis and response to therapy

2021.

Mina Mandic
Biotechnologically relevant enzymes in strains of Pseudomonas genus: Identification and recombinant expression of laccases and lipases

Srđan Boskovic
Characterization of zebrafish ankrd1a, ankrd1b and ankrd2 genes in development and stress response

Vladanka Vukovic
Epigenetic mechanisms regulating the expression of human SOX3 gene and pluripotency factors (SOX2, OCT4 and NANOG) during the early stages of NTera2/D1 cells neural differentiation

2020.

Dragana Bosnic
The role of silicic acid in modulation of oxidative stress responses in cucumber (Cucumis sativus L.) exposed to toxic copper

Jovana Komazec
Coding and noncoding variants of disease-causing genes of maturity-onset diabetes of the young: phenotype modulators and regulators of gene expression

Milka Malesevic
Identification and characterization of biogenic silencers of Pseudomonas aeruginosa quorum sensing 

2019.

Ivana Aleksic
Derivatives of rhamnolipids and 4-aminoquinoline as Pseudomonas aeruginosa and Serratia marcescens virulence inhibitors

Marina Andjelkovic
Genomic profiling of pediatric patients with primary ciliary dyskinesia: genotype- phenotype correlation and functional characterization of novel genetic variants

Vladimir Gasic
Research Assistant in IMGGE, defended his doctoral dissertation entitled Pharmacogenomic and pharmacotranscriptomic markers in glucocorticoid treatment of pediatric acute lymphoblastic leukemia: molecular mechanism of action, clinical and population aspects

Jelena Marjanovic
Analysis of the role of SOX1 and SOX3 genes in promotion of malignant phenotype of glioblastoma cells

Marija Mojicevic
Antifungal potential of streptomycetes isolated from ethno-medicinal plants' rhizospheres: characterization and optimization of staurosporine biosynthesis by Streptomyces sp. BV410 strain

Nikola Popovic
Examination of probiotic and immunomodulatory characteristics of natural isolates of enterococci on in vitro and in vivo models

Marijana Rakonjac
Analysis of speech and language, social-emotional and cognitive development of patients with heterozygous microdeletion of the region q11.2 of chromosome 22

Anita Skakic
Genomic profiling of pediatric patients with liver glycogenosis: genotype-phenotype correlation and functional characterization of novel variants lymphoblastic leukemia: molecular mechanism of action, clinical and population aspects

Svetlana Sokovic Bajic
Characterization of the lactic acid bacteria producers of γ-aminobutyric acid and their role in the prevention and treatment of experimental autoimmune encephalomyelitis

Misa Vreca
Expression of genes associated with inflammation and fibrosis and candidate genes for cell therapy optimization in patients with systemic sclerosis

2018.

Slobodan Davidovic
Analysis of mitochondrial DNA variability of residents of the Republic of Serbia: Population genetics, phylogenetic and phylogeographic perspectives

Miroslav Dinic
Influence of bioactive molecules of lactobacilli on autophagy and inflammation processes in in vitro and in vivo systems

Irena Marjanovic
Identification of molecular genetic markers of acute myeloid leukemia pathogenesis

Dusan Milivojevic
Evaluation of selected virulence factors in Pseudomonas aeruginosa isolates and their susceptibility to silver complexes

Mirjana Novkovic
Analysis of variants in the promoter region of CYP2C19 gene and their role in prediction of clopidogrel response in patients with myocardial infarcition and carotid stenosis

Katarina Novovic
Regulation of gene expression and diversity of CarO and Omp33-36 porins in Acinetobacter spp.  

Danijela Stanisavljevic
Analysis of the expression and role of the human gene SOX14 in neural differentiation in vitro and in the regulation of malignant phenotype

2017.

Sandra Dragicevic
Analysis of the TGFB1 gene promoter variants as risk factors and modulators of response to asthma therapy

Maja Gvozdenov
Functional analysis of FIIc.1787G>A (prothrombin Belgrade) and FIIc.*64_*66del gene variants and their association with thrombophilia

Haowa M. Madi
Genotyping, аntibiotic resistance and biofilm formation of Stenotrophomonas maltophilia clinical isolates from Serbia 

2016.

Jovana Jasnic
Determination of expression profile and localization of ANKRD2 protein in human cardiac and skeletal muscles

Marija Miljkovic
Characterization of AggLb aggregation factor from strain Lactobacillus paracasei subsp. paracasei BGNJ1-64

Nemanja Mirkovic
Characterization and determination of bacteriocins produced by autochthonous lactococci

Jelena Radivojevic
Poly(hydroxyalkanoate) monomers as source for biological active compounds synthesis

Srdjan B. Stankovic
Microbial diversity of an extremely acidic lake Robule and effect of lake water on oxidation of sulfide minerals

Zorica Vasiljevic

Goran Vukotic
Proteinases of lactic acid bacteria: Diversity in mesophilic species of lactobacilli and impact on bacteriocin activity 

2015.

Nemanja Stanisavljevic
Characterization and in vitro biological activities of phenolic compounds from pea (Pisum sativum L.)

Kristel Klaassen
Impact of variants in coding and noncoding regions of disease-causing and modifier genes on phenotype of patients with hyperphenylalaninemia

Nikola Kotur
Pharmacogenetics of 6-mercaptopurine and methotrexate in childhood acute lymphoblastic leukemia

Biljana Stankovic
Molecular markers of chronic inflammation and apoptosis in inflammatory bowel diseases

Sanja Srzentic
Molecular markers of impaired coagulation, inflammation, apoptosis, formation and bone remodeling processes in Legg-Calve-Perthes disease

2014.

Milena Milivojevic
The role of Sonic Hedgehog signaling pathway in the regulation of SOX18 gene expression in HeLa cells, model system of cervical carcinoma

Iva Pruner
The functional analysis of the C20068T gene variant in the 3'end of the prothrombin gene and its role in the pathogenesis of thrombophilia

Gordana Uzelac
Characterisation of bacteriocins of lactic acid bacteria and mechanisms of action on sensitive cells

2013.

Brankica Filipic
Functional characterization of the CmbT transporter responsible for multidrug resistance on structurally different substrates of the strain Lactococcus lactis subsp. cremoris MG1363

Bojana Banovic
Molecular basis of self-incompatibility system in buckwheat (Fagopyrum esculentum Moench)

Sanja Jeremic
Mechanisms of heavy metal tolerance in free living bacteria and bacterial biofilms

Jovanka Lukic
Analysis of interactions of lactobacilli with rat gut mucosa

Zivko Jovanovic
The role of DREB2A transcription factor and small RNAs mir398a/b and mir408 in dehidration response of pea (Pisum sativum L.)

2012.

Branka Borovic
Molecular and technological characterisation of lactic acid bacteria isolated from dry fermented sausages produced in traditional way

Teodora Karan-Djurasevic
Molecular basis of chronic lymphocytic leukemia: correlation between the immunoglobulin heavy chain mutational status and the expression of apoptotic genes

Gordana Kozoderovic
Analysis of nature of resistance to quinolones and molecular typing of selected serotypes of Salmonella enterica subspecies enterica

Mila Ljujic
Structural and functional analysis of alpha-1-antitrypsin gene in human lung diseases

Tanja Narancic
Metabolic versatility of bacteria isolated from surface river sediment influenced by petrochemical effluents: The case of Pseudomonas sp. TN301 as polyhydroxyalkanoate producer

Aleksandra Nestorovic
Regulatory role of hAnkrd1 protein: interaction with transcription factors and signaling proteins

Milica Nikolic
Characterization of surface molecules from bacterial cells involved in the potential probiotic activity of natural lactobacilli isolates

Aleksandar Pavic
Functional diversity of bacterial communities isolated from truffle's fruit bodies

Isidora Petrovic
Transcriptional regulation of the human SOX18 gene expression

Vesna Spasovski
Molecular  mechanisms  of  pathogenesis  of  myeloproliferative  neoplasms: deregulation of genes involved in cell proliferation and apoptosis

Nada Stankovic
Isolation and characterization of bioactive secondary metabolites from selected Streptomyces strains

Maja Tolinacki
Correlation between the presence of bacteriocin genes and bacteriocin production in natural isolates of Lactobacillus casei/paracasei group

Branko Tomic
Structure of topologically closed ORI sequence from dihydrofolate reductase locus in interaction with initiation protein ORC

2011.

Goran Cuturilo
Comparative analysis of molecular and molecular-cytogenetic approach in the analysis of microdeletion 22q11.2 in patients with syndromic forms of congenital heart malformations

Danijela Drakulic
Analysis of effects of SOX2 overexpression on pluripotency, proliferation and neural differentation of embryonal carcinoma NT2/D1 cells

Milena Radmilovic
Modifier genes of b-thalassemia syndromes: gene variants as regulators of gene expression and population-genetic markers.

Katarina Veljovic
Antimicrobial activity of enterococci isolated from fermented products and cloning of genes for synthesis and immunity of the chosen enterocin

Sandra Vojnovic
Regulation of expression of kgmB gene from Streptomyces tenebrarius

Gordana Zavisic Opacic
Molecular and physiological characterisation of the potential probiotic strains of Lactobacillus sp.

2010.

Tanja Beric
Biochemical and molecular genetic characterization of Bacillus sp. isolates from the territory of Serbia

Milos Busarcevic
Molecular characterization of bacteriocins produced by natural isolate Lactobacillus salivarius BGHO1

Lidija Djokic
Metagenomic approach in microbial biodiversity analysis of endemorelict plants` rhizospheres and isolation of phenol degrading bacteria

Valentina Djordjevic
Analysis of human prothrombin gene 3' end influence on prothrombin gene expression and pathogenesis of thrombophilia

Tatjana Ilic-Tomic
Research of translational autoregulation of the sgm gene in vitro

Natasa Jokovic
Diversity of lactic acid bacteria isolated from kaymak

Aleksandra Nikolic
Structural and functional analysis of smad4 gene 5' regulatory region in human pancreatic cancer

Dragana Nikolic
Regulation of gene expression of metallothionein type 3 and buckwheat protein MT3 role in defending the plant tissues from stress induced by heavy metals

Jelena Popovic
Transcriptional regulation of human SOX14 gene expression

Ljiljana Rakicevic
Functional analysis of hAnkrd2 protein: regulation of expression and activity

Nataša Tosic
The interaction of genetic markers of proliferation, differentiation and apoptosis in acute leukemias

Jelena Samardzic
Analysis of expression and functions of metallothionein type 3 from buckwheat (Fagopyrum esculentum Moench)

Marija Stankovic
Analysis of genetic variants in chronic obstructive pulmonary disease in humans

Branka Zukic
Components of human thiopurine S-methyltransferase gene expression regulation system as pharmacogenetic markers

2009.

Branko Jovcic
Cloning and molecular analysis of Pseudomonas sp. ATCC19151 sulphatase operons

Nataša Kovacevic Grujicic
Characterization of the basal promoter of the human SOX3 gene and identification of the regulatory elements responsible for the SOX3 gene induction by retinoic acid

Mira Milisavljevic
Analyses of expression, activity and localization of the new type of aspartic proteinase (FeAPL1) from buckwheat (Fagopyrum esculentum Moench)

Maja Stojiljkovic
Variants in human phenylalanine hydroxylase gene as gene expression regulators, phenotype modulators and population-genetic markers

Gordana Timotijevic
Molecular cloning and analysis of the aspartic proteinase gene from buckwheat (Fagopyrum esculentum Moench)

Jelena Urosevic
Study of the role of B-Raf protein in cancer using animal tumor model systems

2008.

Jelena Begovic
Molecular characterization of human vaginal lactobacilli resistant to antibiotics

Aleksandra Divac
Structural changes of  DNA mediated by protein HsOrc4

Jelena Lozo
Molecular characterization of bacteriocin and aggregation ability of a natural isolate Lactobacillus paracasei subsp. paracasei BGSJ2-8

Marija Mojsin
The role of TALE transcription factors in the retinoic acid induced activation of SOX3 gene

2006.

Ivana Moric
The application of X ray microscopy in elemental mapping of Mycobacterium avium pks12 mutant

2005.

Jelena Kusic
Interaction of initiation ORC protein and lamin B2 replicator

Milica Sevo
Molecular analysis of three alternative sigma factors of Pseudomonas aeruginosa PAO1

2003.

Jelena Brkljacic
Cloning and analysis of the regulation of gene expression of the metallothionein buckwheat (Fagopyrum esculentum Moench)

Snezana Kojic
Characterization of human skeletal muscle protein Ankrd2

Marina Lusic
Molecular analysis of the changes following transcriptional activation of the HIV-1 LTR promoter

Irena Pastar
Molecular analysis of proteinase gene from human isolate Lactobacillus rhamnosus BGT10

Slavica Stanojcic
Interaction of initiation proteins with ori-sequence lamin B2

Ivana Strahinic
Characterization of natural isolate Lactobacillus sp. BGRA43 as a potential probiotic

2002.

Milija Jovanovic
Analysis of the expression of a gene that provides resistance to antibiotic novobiocin in Escherichia coli K12  

Maja Vukasinovic
Influence of proteolytic enzymes activity of lactic acid bacteria on fermentation of semi-hard cheese

2001.

Tatjana Kostic
Molecular basis of genetic rearrangements induced by IS5 elements in polA1 mutator strain of E.coli K12

Sonja Pavlovic
Molecular genetics of thalassemia syndromes: correlation between molecular pathology and phenotype

2000.

Radmila Janjusevic
Regulation of cls gene expression in Escherichia coli K12

Aleksandra Trifunovic
Identification and molecular characterisation of albumin-like protein in red blood cells (RBC) of Belgrade laboratory (b/b) rat

1999.

Natasa Miladinov
Analyses of prt genes regulation in the natural isolate Lactococcus lactis subsp. lactis BGIS29

Suzana Savkovic
Regulation of gene expression and physiological functions of the intestinal epithelial cells in the presence of enteropathogenic bacteria

1998.

Djordje Fira
Characterization of extracellular proteinases of bacteria from Staphylococcus and Lactobacillus genera

Mira Lilic
Regulation of the expression of a new gene responsible for drug resistance of Escherichia coli K12 to the antibiotic novobiocin

Gordana Nikcevic
The effect of expression of the catalytic domain of myosin light chain kinase on the contractile properties of non-muscle cells

Svetlana Radovic
Characterization of storage proteins from buckwheat seeds

1997.

Vesna Maksimovic
Biosynthesis of buckwheat seed storage proteins

Dragica Radojkovic
Prenatal diagnostics of cystic fibrosis by DNA analysis

Zorica Scuric
The analysis of differential gene expression in human hepatocellular carcinoma

1996.

Goran Ljubijankic
Posttranslational processing of prokaryotic Penicillin G amidase in a eukaryotic cell yeast Saccharomyces cerevisiae

Jelena Zaric
Changes in membrane proteins of Belgrade laboratory rat

1995.

Dragana Ajdic
The galactose operon of Streptococcus mutans

Milan Kojic
Analysis of large conjugative plasmid of Lactococcus lactis subsp. lactis biovar. diacetylacticis S50

1994.

Branka Dabovic
Fine mapping and positional cloning of genes from Xq13 region (DXS56 - PGK1) of the human X chromosome

Milorad Kojic
Analysis of regulatory regions and expression of the sgm gene from Micromonospora zionensis

1993.

Ivan Brukner
Structural polymorphism of DNA

1991.

Maja Krajinovic
Investigations of the frequency of human papilloma viruses and their role in the development of benign and malignant tumors of the cervix

1990.

Miroslav Konstantinovic
Properties of in vitro constructed DNA elements responsible for gene activity cloned in Escherichia coli - performance of the new PltI promoter

Milena Stevanovic
Structural analysis of three haplotypes of β globin gene family encoding globine chains of hemoglobin in rats Rattus Norvegicus

1988.

Radoje Drmanac
The development of an original method for determining the primary structure of the genome using hybridization with oligonucleotide probe

Branka Vasiljevic
Mechanisms of resistance and fidelity of translation in aminoglycoside-resistant bacteria

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