Senior Research Associate
Laboratory for Molecular Biology (LMB)

Institute of molecular genetics and genetic engineering (IMGGE),
University of Belgrade

V. Stepe 444a, P.Fah 23, 11010 Belgrade, Serbia
Mobile:  +381 64 3976658                            
Phone:  +381 11 3976658
Fax:      +381 11 397 58 08
E-mail: kobran@imgge.bg.ac.rs

EDUCATION

2012 - PhD in Molecular Genetics and Genetic Engineering, Faculty of Biology (FB), UB
(Structure of topologically closed ori sequence from dihydrofolate reductase locus in interaction with initiation protein ORC)
2005 - B.Sc. in Molecular Biology and Physiology, FB, University of Belgrade

RESEARCH EXPERIENCE

2018 - Senior Research Associate, IMGGE, UB
2013-2018 - Research Associate, IMGGE, UB
2007 - 2013 - Research Assistant, LMB, IMGGE
2005 - 2007 - Research Trainee, LMB, IMGGE

CAREER HISTORY

2016 - Head of Sector for Laboratory Examinations IMGGE
2013 - Lecturer on Faculty of Biology, UB

RESEARCH INTEREST

prothrombin 3'end processing and regulation of prothrombin gene expression

DNA-protein interactions,functional analysis of 3'end prothrombin gene variants

3'end of prothrombin gene  in etiology of thrombophilia, cancer, inflammation

screening for new thrombophilia markers inherited thrombophilia

SELECTED PUBLICATIONS

Determination of transgene copy number in stably transfected mammalian cells by PCR-capillary electrophoresis assay. Pruner I, Djordjevic V, Gvozdenov M, Tomic B, Radojkovic D. Biochem Genet. 2014 Apr;52(3-4):159-65. [http://www.ncbi.nlm.nih.gov/pubmed/24292648]

The 3'end prothrombin gene variants in patients with different thrombotic events. Djordjevic V, Pruner I, Tomic B, Nestorovic A, Gvozdenov M, Kovac M, Radojkovic D. Lab Med. 2014 Fall;45(4):309-14 [ http://www.ncbi.nlm.nih.gov/pubmed/25316662]

Human initiation protein Orc4 prefers triple stranded DNA. Kusic J, Tomic B, Divac A, Kojic S.

Mol Biol Rep. 2010 Jun;37(5):2317-22.

[http://www.ncbi.nlm.nih.gov/pubmed/19690980]

Novel ORC4L gene mutation in B-cell lymphoproliferative disorders. Radojkovic M, Ristic S, Divac A, Tomic B, Nestorovic A, Radojkovic D.Am J Med Sci. 2009 Dec;338(6):527-9.

[http://www.ncbi.nlm.nih.gov/pubmed/20010161]

Formation of noncanonical DNA structures mediated by human ORC4, a protein component of the origin recognition complex. Stefanovic D, Kusic J, Divac A, Tomic B. Biochemistry. 2008 Aug 19;47(33):8760-7.

[http://www.ncbi.nlm.nih.gov/pubmed/18652488]

Analysis of common CFTR polymorphisms 5T, M470V and R75Q in healthy Serbian population. Nikolic A, Divac A, Stankovic M, Dinic J, Tomic B, Ljujic M. Genetika. 2006 Jul;42(7):996-8.

[http://www.ncbi.nlm.nih.gov/pubmed/16915933