Non-small cell lung cancer is one of the most common and serious forms of lung cancer, making reliable biomarkers important for timely detection and more accurate diagnosis. This study demonstrated that the level of RNA transcribed from the SMAD4 gene is reduced in non-small cell lung cancer tissue. The findings indicate the potential of this biomarker, which, alongside existing diagnostic methods, could be used as an additional tool for the earlier and more accurate detection of lung cancer.

The study was conducted in collaboration with colleagues from Institute for Biological Research „Siniša Stanković“.

SMAD4 mRNA expression as a diagnostic biomarker in non-small cell lung cancer

Gene Regulation in Cancer Group