Marina Andjelkovic
Assistant Research Professor
Laboratory for Molecular Biomedicine
GROUP FOR RARE DISEASE RESEARCH AND THERAPEUTICS DEVELOPMENT
Institute of molecular genetics and genetic engineering (IMGGE),
University of Belgrade
Vojvode Stepe 444a, 11042 Belgrade 152, Serbia
Mobile: +381 65 397 64 45
Phone: +381 11 397 64 45
Fax: +381 11 397 58 08
E-mail: marina.andjelkovic@imgge.bg.ac.rs
EDUCATION
2019 - PhD in Molecular Biology, Faculty of Biology (FB), University of Belgrade (UB)
(Thesis: " Genomic profiling of pediatric patients with primary ciliary dyskinesia: genotype- phenotype correlation and functional characterization of novel genetic variants”.
2014 – Master of Science in Molecular biology and physiology, FB, UB
2013 - Diploma in Molecular biology and physiology, FB, UB
RESEARCH EXPERIENCE
2020 - Research Associate at Laboratory for Molecular Biomedicine, IMGGE, UB
2016 - 2020 Research Assistant, Laboratory for Molecular Biomedicine, Institute of molecular genetics and genetic engineering, UB
2014 - 2016 - Research Trainee at Laboratory for Molecular Biomedicine, IMGGE, UB
OTHER ACTIVITIES
2022 – 2023 - Analysis of the synergistic effect and therapeutic potential of small molecules in patients with recurrent pulmonary infections (Innovation fond, Republic of Serbia, TT1104) – Principal Investigator
2020 – 2021 - Analysis of the synergistic effect and therapeutic potential of small molecules in patients with recurrent pulmonary infections (Innovation fond, Republic of Serbia, PoC 5269) – Principal Investigator
2019 – 2023 - European Network for Innovative Diagnosis and Treatment of Chronic Neutropenias (EuNet-INNOCHRON, funded by The European Cooperation in Science and Technology, COST ACTION 18233) – participant;
2013 – 2019 - Rare diseases: Molecular Pathophysiology, Diagnostic and Therapeutic Modalities and Social, Ethical and Legal Aspects, (MESTD RS, III41004) – participant;
2014 – 2015 - Science in motion for Friday Night commotion “SCIMFONICOM 2014-2015” (H2020-MSCA-NIGHT-2014 Researchers' night, Grant: 633376) – participant;
2013 – 2016 - Strengthening the Research Potential of IMGGE through Reinforcement of Biomedical Science of Rare Diseases in Serbia – en route for innovation, SERBORDISinn”, funded by European Commission (EU-FP7-REGPOT, 316088, 2013-2016) – participant.
2013 - “Little school of DNAlogy”, grant from MESTD RS
2014 - Researcher in Laboratory for Molecular Biomedicine, IMGGE, UB
RESEARCH INTEREST
The field of my scientific interest includes pediatric pulmonary diseases, primarily primary ciliary dyskinesia (PCD). PCD is inherited in an autosomal recessive manner, and predominantly affects the respiratory tract and reproductive organs, and affects the laterality of the internal organs. Genomic profiling of patients with this disorder enabled the establishment of a precise diagnosis of PCD, but also a differential diagnosis of this disease from other pediatric lung diseases with a similar clinical presentation. Comprehensive genomic profiling enabled design of genetic algorithm which in addition to the known disease-causing genes, includes candidate genes and newly discovered genetic variants, as well as genes responsible for the individual symptoms of this disease and the genes responsible for ciliopathies, thereby improving the effectiveness of mutation detection rate and establishing a genetic diagnosis of the disease.