Vesna Spasovski

Research Associate
Laboratory for Molecular Biomedicine

Institute of Molecular Genetics and Genetic Engineering (IMGGE),
University of Belgrade (UB)

V. Stepe 444a, P.Fah 23, 11010 Belgrade, Serbia
Mobile:     +381 65 3976445                          
Phone:     +381 11 3976445
Fax:         +381 11 397 58 08
E-mail: vesna.spasovski@imgge.bg.ac.rs

EDUCATION

2012 - PhD in Molecular Genetics and Genetic Engineering, Faculty of Biology, University of Belgrade (Molecular mechanisms of pathogenesis of myeloproliferative neoplasms: deregulation of genes involved in cell proliferation and apoptosis)
1997 - B.Sc. in Molecular Biology, Faculty of Biology, University of Belgrade

RESEARCH EXPERIENCE

2013 - Research Associate, Laboratory for Molecular Biomedicine, IMGGE, University of Belgrade
2010 - 2013 - Research Assistant, Laboratory for Molecular Biomedicine, IMGGE, University of Belgrade
2009 - 2010 - Research Trainee, Laboratory for Molecular Biomedicine, IMGGE, University of Belgrade

CAREER HISTORY

2012 - work package leader „Rare diseases in orthopedics: molecular basis of Perthes disease“ in project „ Rare diseases: Molecular Pathophysiology, Diagnostic and Therapeutic Modalities and Social, Ethical and Legal Aspects “ (MPNTR, III 41004, 2011-2015)
2011 - work package leader, Researchers night “RENIFEVER” (EU, CSA-SA, FP7-PEOPLE-2011-NIGHT-287432, 2011.)
2009 - 2012 - involved in the project “Little school of DNAlogy” (MSTDS)
2003 - 2004 - Medical Genetic Section, Institute of Mental Health, Belgrade
2002 - 2003 - Laboratory for Cytogenetics and Molecular Genetics, Clinics for hematology, Clinical Center of Serbia
2001 - 2002 - Laboratory for Neurobiology, Max Plank Institute, Munich
1998 - 2001 - Master studies, Faculty of Biology, UB

RESEARCH INTEREST

More recent work has been focused on treatment of orthopedic and rheumatic diseases using technology of stem cells. The main research interest are autoimmune and rheumatic diseases, with a focus on shedding light on etiology, improvement of diagnostic procedures and therapy of these disorders. Another research focus is investigation of genetic basis of pulmonology disorders.

SELECTED PUBLICATIONS

  1. Škodrić-Trifunović V, Stjepanović M, Savić Ž, Ilić M, Kavečan I, Jovanović Privrodski J, Spasovski V, Stojiljković M, Pavlović S. Novel Patched 1 mutations in patients with nevoid basal cell carcinoma syndrome - case report. Croat Med J. 2015 Feb 28;56(1):63-7.
  2. Srzentic S, Nikcevic G, Spasovski D, Bascarevic Z, Zivkovic Z, Terzic-Supic Z, Matanovic D, Djordjevic V, Pavlovic S and Spasovski V. Predictive genetic markers of coagulation, inflammation and apoptosis in Perthes disease - Serbian experience
  3. Škodrić-Trifunović V, Buha I, Jovanović D, Vučinić V, Stjepanović M,  Spasovski V, Andjelković M, Vreća M, Skakić A, Gašić V, Pavlović S.Variants in VDR and NRAMP1 genes as suspetibility factors for tuberculosis in the population of Serbia. Genetika 2015 47 (3), 1021-1028
  4. Jančić I I, Šefik-Bukilica M, Živojinović S, Damjanov N, Spasovski V, Kotur N, Klaassen K, Pavlović S, Bufan B, Arsenović-Ranin N. Influence Of Promoter Polymorphisms Of The Tnf-α (-308g/A) And IL-6 (-174g/C) Genes On Therapeutic Response To Etanercept In Rheumatoid Arthritis Journal of Medical Biochemistry 2015 34 (4), 414-421
  5. Srzentić S, Spasovski V, Spasovski D, Zivković Z, Matanović D, Bascarević Z, Supić ZT, Stojiljković M, Karan-Djurasević T, Stanković B, Pavlović S, Nikcević G, Vukasinović Z. Association of gene variants in TLR4 and IL-6 genes with Perthes disease. Srp Arh Celok Lek. 2014 Jul-Aug;142(7-8):450-6.
  6. Spasovski V, Tosic N, Nikcevic G, Stojiljkovic M, Zukic B, Radmilovic M, Karan-Djurasevic T, Srzentic S, Colovic M, Pavlovic S. The influence of novel transcriptional regulatory element in intron 14 on the expression of Janus kinase 2 gene in myeloproliferative neoplasms. J Appl Genet. 2013 Feb;54(1):21-6
  7. Jančić I, Arsenović-Ranin N, Sefik-Bukilica M, Zivojinović S, Damjanov N, Spasovski V, Srzentić S, Stanković B, Pavlović S. -174G/C interleukin-6 gene promoter polymorphism predicts therapeutic response to etanercept in rheumatoid arthritis. Rheumatol Int. 2013 Jun;33(6):1481-6
  8. Vukasinovic Z, Spasovski D, Kralj-Iglic V, Marinkovic-Eric J, Seslija I, Zivkovic Z, Spasovski V. Impact of triple pelvic osteotomy on contact stress pressure distribution in the hip joint Int Orthop. 2013 Jan;37(1):95-8.
  1. Karan-Djurašević T, Palibrk V, Zukić B, Spasovski V, Glumac I, Čolović M, Čolovic N, Jurisic V, Scorilas A, Pavlović S, Tošić N. Expression of Bcl2L12 in chronic lymphocytic leukemia patients: association with clinical and molecular prognostic markers. Med Oncol. 2013; 29(1):260-262.
  2. Djordjević M, Klaassen K, Sarajlija A,Tošić N, Zukić B, Kecman B, Ugrin M, Spasovski V, Pavlović S, Stojiljković M. Molecular Genetics and Genotype-Based Estimation of BH4-Responsiveness in Serbian PKU Patients: Spotlight on Phenotypic Implications of p.L48S. J Inh Met Dis Reports. 2012; 
  3. Karan-Djurasevic T, Palibrk V, Kostic T, Spasovski V, Nikcevic G, Srzentic S, Colovic M, Colovic N, Vidovic A, Antic D, Mihaljevic B, Pavlovic S, Tosic N. Mutational status and gene repertoire of IGHV-IGHD-IGHJ rearrangements in Serbian patients with chronic lymphocytic leukemia. Clinical Lymphoma Myeloma and Leukemia 2012; 12 (4): 252-260.
  4. Kuzmanović M, Tošić N, Čolović N, Karan-Djurašević T, Spasovski V, Radmilović M, Nikčević G, Suvajdzić-Vuković N, Tomin D, Vidović A, Virijević M, Pavlović S, Čolović M. Prognostic Impact of NPM1 Mutations in Serbian Adult Patients with Acute Myeloid Leukemia. Acta Haematol. 2012; 128(4):203-212.
  5. Stojiljković M, Zukić B, Tošić N, Karan-Djurašević T, Spasovski V, Nikčević G, Pavlović S. Novel transcriptional regulatory element in the phenylalanine hydroxylase gene intron. Mol Genet Metab. 2010; 101(1):81-83.
  6. Radmilovic M, Zukic B, Stankovic B, Karan-Djurasevic T, Stojiljkovic M, Spasovski V, Tosic N, Dokmanovic L, Janic D, Pavlovic S. Thalassemia syndromes in Serbia: an update. Hemoglobin 2010; 34(5): 477-85.
  7. Krstovski N, Tošić N, Janić D, Dokmanović L, Kuzmanović M, Spasovski V, Pavlović S.Incidence of FLT3 and nucleophosmin gene mutations in childhood acute myeloid leukemia: Serbian experience and the review of the literature. Med Oncol. 2010; 27(3):640-645.
  8. Spasovski V, Tosić N, Kostić T, Pavlović S, Colović M.JAK2-V617F mutation in patients with myeloproliferative neoplasms: association with FLT3-ITD mutation. Srp Arh Celok Lek. 2010; 138(9-10):614-618.
  9. Spasovski V, Tošić N, Kostić T, Zukić B, Stojiljković M, Čolović M, Pavlović S. The Role of FASR/FASL system in pathogenesis of myeloproliferative neoplasms. Arch biol sci. 2010; 62(2):223-230.

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