Vladanka Vuković

Istraživač saradnik
Laboratorija za humanu molekularnu genetiku

Institut za molekularnu genetiku i genetičko inženjerstvo (IMGGI),
Univerzitet u Beogradu,

V. Stepe 444a, 11010 Beograd, Srbija
Mob:   +381 65 3976 212
Tel:     +381 11 3976 212
Fax:    +381 11 397 58 08
E-mail: vladankatopalovic@imgge.bg.ac.rs                                   

OBRAZOVANJE

2011 - Student doktorskih studija, BF, UB
2011 - Diplomirani molekularni biolog i fiziolog, BF, UB

ISTRAŽIVAČKO ISKUSTVO

2014 - Istraživač saradnik, IMGGI, UB
2012 - 2014 - Istraživač pripravnik, IMGGI, UB

RADNO ISKUSTVO

2012 - Istraživač, Laboratorija za humanu molekularnu genetiku, IMGGI, UB
2013-2014 - stipendista Erasmus Mundus Sigma programa, Department of BioSciences, University of Milan, Milano, Italija
2010 - stipendista Letnje istraživačke škole, École polytechnique fédérale de Lausanne, Lozana, Švajcarska           

OBLAST NAUČNOG INTERESOVANJA

  • Analiza uloge epigenetičkih mehanizama u regulaciji ekspresije humanih SOXB1 gena tokom procesa neuralne diferencijacije
  • Izučavanje interakcija Wnt signalnog puta i humanih SOXB1 gena
  • Analiza molekularnog diverziteta srpske populacije bazirana na polimorfizmima mitohondrijalne DNK

ODABRANI NAUČNI RADOVI

Marjanovic Vicentic J, Drakulic D, Garcia I, Vukovic V, Aldaz P, Puskas N, Nikolic I, Tasic G, Raicevic S, Garros-Regulez L, Sampron N, Atkinson MJ, Anastasov N, Matheu A, Stevanovic M. SOX3 can promote the malignant behavior of glioblastoma cells. Cell Oncol (Dordr). 2019 42(1):41-54. https://www.ncbi.nlm.nih.gov/pubmed/30209685

Epigenetic regulation of human SOX3 gene expression during early phases of neural differentiation of NT2/D1 cells. Topalovic V, Krstic A, Schwirtlich M, Dolfini D, Mantovani R, Stevanovic M, Mojsin M. PLoS One. 2017 Sep 8;12(9):e0184099. doi: 10.1371/journal.pone.0184099. eCollection 2017. https://www.ncbi.nlm.nih.gov/pubmed/28886103

Histone Modifications on the Promoters of Human OCT4 and NANOG Genes at the Onset of Neural Differentiation of NT2/D1 Cells.Topalovic V, Schwirtlich M, Stevanovic M, Mojsin M. Biochemistry (Mosc). 2017 Jun;82(6):715-722. doi: 10.1134/S0006297917060086. https://www.ncbi.nlm.nih.gov/pubmed/28601081

SOX14 activates the p53 signaling pathway and induces apoptosis in a cervical carcinoma cell line. Stanisavljevic D, Petrovic I, Vukovic V, Schwirtlich M, Gredic M, Stevanovic M, Popovic J. PLoS One 2017;12(9): e0184686  https://www.ncbi.nlm.nih.gov/pubmed/28926586 

Davidovic S, Malyarchuk B, Aleksic J, Derenko M, Topalovic V, Litvinov A, Skonieczna K, Rogalla U, Grzybowski T, Stevanovic M, Kovacevic-Grujicic N. Mitochondrial super-haplogroup U diversity in Serbians. Ann Hum Biol. 2017 Aug;44(5):408-418. doi: 10.1080/03014460.2017.1287954. Epub 2017 Feb 19. https://www.ncbi.nlm.nih.gov/pubmed/28140657

Crosstalk between SOXB1 proteins and WNT/β-catenin signaling in NT2/D1 cells Mojsin M, Topalovic V, Vicentic JM, Schwirtlich M, Stanisavljevic D, Drakulic D, Stevanovic M. Histochem Cell Biol. 2015 Nov;144(5):429-41. doi: 10.1007/s00418-015-1352-0. Epub 2015 Aug 4. https://www.ncbi.nlm.nih.gov/pubmed/26239426

Antioxidant and antiproliferative activity of chokeberry juice phenolics during in vitro simulated digestion in the presence of food matrix. Stanisavljevic N, Samardzic J, Jankovic T, Savikin K, Mojsin M, Topalovic V, Stevanovic M. Food chem. 2015 May;175:516-522  http://ac.els-cdn.com/S0308814614019116/1-s2.0-S0308814614019116-main.pdf?_tid=44e577e2-b75b-11e4-937d-00000aab0f6b&acdnat=1424256515_db1895d6fdbe1d34fae900177e85c809

Transcription  factor  NF-Y inhibits  cell  growth and decreases SOX2 expression in  humanembryonal  carcinoma  cell  line  NT2/D1.  M.  Mojsin,  V.  Topalovic,  J.  Marjanovic  and  M.Stevanovic, Biochemistry (Moscow). 2015 Jan 25;80:202-207 https://www.ncbi.nlm.nih.gov/pubmed/25756534 

Mitochondrial DNA perspective of Serbian genetic diversity. Davidovic S, Malyarchuk B, Aleksic JM, Derenko M, Topalovic V, Litvinov A, Stevanovic M, Kovacevic-Grujicic N, Am J Phys Anthropol. 2014 Nov 24. doi: 10.1002/ajpa.22670.  http://www.ncbi.nlm.nih.gov/pubmed/?term=Mitochondrial+DNA+perspective+of+Serbian+genetic+diversity

Quercetin reduces pluripotency, migration and adhesion of human teratocarcinoma cell line NT2/D1 by inhibiting Wnt/β-catenin signaling. Mojsin M, Vicentic JM, Schwirtlich M, Topalovic V, Stevanovic M, Food Funct. 2014 Oct 24;5(10):2564-73 http://www.ncbi.nlm.nih.gov/pubmed/25138740

Cyclic AMP response element binding (CREB) protein acts as a positive regulator of SOX3 gene expression in NT2/D1 cells. Kovacevic-Grujicic N, Mojsin M, Popovic J, Petrovic I, Topalovic V, Stevanovic M. BMB Rep 2014; 47: 197-202 https://www.ncbi.nlm.nih.gov/pubmed/24257117 

Quercetin and lithium chloride modulate Wnt signaling in pluripotent embryonal carcinoma NT2/D1 cells. Mojsin M, Topalovic V, Marjanovic J, Stevanovic M. Archives of Biological Sciences, 2013; 65(1); 201-209 http://www.doiserbia.nb.rs/Article.aspx?ID=0354-46641301201M#.VE9nmDTF-2Y 

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