Jelena Kušić-Tišma

Naučni saradnik
Laboratorija za molekularnu biologiju (LMB)

Institut za molekularnu genetiku i genetičko inženjerstvo (IMGGI),
Univerzitet u Beogradu,

V. Stepe 444a, 11010 Beograd, Srbija
Tel:     +381 11 3976658
Fax:    +381 11 397 58 08
E-mail: jkusic@imgge.bg.ac.rs                                   

OBRAZOVANJE

2005 - Doktor bioloških nauka, Biološki fakultet, Univerzitet u Beogradu
1999 - Magistar bioloških nauka Biološki fakultet, Univerzitet u Beogradu
1995 - Diplomirani biolog, Biološki fakultet, Univerzitet u Beogradu

ISTRAŽIVAČKO ISKUSTVO

2005 - naučni saradnik, Institut za molekularnu genetiku i genetičko inženjerstvo, Univerzitet u Beogradu
1996 - 2005 - istraživač saradnik, Institut za molekularnu genetiku i genetičko inženjerstvo, Univerzitet u Beogradu
1995 - 1996 - istraživač pripravnik, Institut za molekularnu genetiku i genetičko inženjerstvo, Univerzitet u Beogradu

RADNO ISKUSTVO

2007 - predavač na doktorskim studijama na Biološkom fakultetu

OBLAST NAUČNOG INTERESOVANJA

Korelacija genotipa i fenotipa kod pacijenata sa hipertrofičnom kardiomiopatijom (HCM), kao i uloga proteina CARP1 u etiologiji HCM. Takođe, primena FRAP i FRET tehnika u ispitivanju dinamičkih karakteristika proteina.

ODABRANI NAUČNI RADOVI

  1. Novkovic M, Matic D, Kusic-Tisma J, Antonijevic N, Radojkovic D, Rakicevic L (2018) Analysis of the CYP2C19 genotype associated with bleeding in Serbian STEMI patients who have undergone primary PCI and treatment with clopidogrel. Eur J Clin Pharmacol 74 (4): 443-451 DOI 10.1007/s00228-017-2401-5
  2. Backovic D, Ignjatovic S, Rakicevic L, Novkovic M, Kusic-Tisma J, Radojkovic D, Strugarevic E, Calija B, Radak D, Kovac M (2016) Clopidogrel High On-Treatment Platelet Reactivity in Patients with Carotid Artery Stenosis Undergoing Endarterectomy. A Pilot Study. Curr Vasc Pharmacol 14 (6): 563-569
  3. Bačković D, Ignjatović S , Rakićević L, Kusić-Tišma J, Radojković D, Čalija B, Strugarević E, Radak D, Kovač M. (2015) Influence of CYP2C19*2 gene variant on therapeutic response during clopidogrel treatment in patients with artery stenosis. J Med Biochem 34: 1–8, 2015; DOI: 10.1515/jomb-2015-0009.
  4. Tomic B, Kusic-Tisma J. (2015) HsOrc4-Dependent Dna Remodeling of the ori-β Dhfr Replicator. Cell Mol Biol Lett. 20(4):549-61. doi: 10.1515/cmble-2015-0032.
  5. Kovac MK, Rakicevic LB, Kusic-Tisma J, Radojkovic DP. (2013). Pharmacogenetic tests could be helpful in predicting of VKA maintenance dose in elderly patients at treatment initiation. J Thromb Thrombolysis. 35(1): 90-94
  6. Rakicevic LB, Kusic-Tisma J, Kovac MK, Backovic DT, Radojkovic DP. (2013) Rationalized DNA sequencing-based protocol for genotyping patients receiving coumarin therapy. Scand J Clin Lab Invest.; 73(6): 523-527.
  7. Kusic-Tisma Jelena and Stefanovic Dragana (2011). Replication Origin Selection and Pre-Replication Complex Assembly, DNA Replication-Current Advances, Dr Herve Seligmann (Ed.), ISBN: 978-953-307-593-8, InTech, DOI: 10.5772/21485.
  8. Divac A, Tomic B, Kusic J. The role of ATP in human ORC4 protein function. J Serb Chem Soc (2010) 75(3):317-322
  9. Кusic, J., Tomic, B., Divac, A., & Kojic, S. (2010). Human initiation protein Orc4 prefers triple stranded DNA. Molecular Biology Reports, 37(5), 2317-2322.
  10. Stankovic M, Nikolic A, Divac A, Tomovic A, Petrovic-Stanojevic N, Andjelic, M, Dopudja-Pantic V, Surlan M, Vujicic I, Ponomarev D, Mitic-Milikic M, Kusic J, Radojkovic, D. (2008). The CFTR M470V gene variant as a potential modifier of COPD severity: Study of serbian population. Genetic Testing, 12(3), 357-362
  11. Stefanovic D, Kusic J, Divac A, Tomic B. Formation of noncanonical DNA structures mediated by human ORC4, a protein component of the origin recognition complex. Biochemistry (2008) 47:8760-8767 PubMed
  12. Dinic J, Kusic J, Nikolic A, Divac A, Ristanovic M. (2006) Radojkovic D Analysis of Y chromosome microdeletions and CFTR gene mutations as genetic markers of infertility in Serbian men. Vojnosanit Pregl. 64(4):253-6.
  13. Kusic J, Kojic S, Divac A, Stefanovic D. (2005). Noncanonical DNA elements in the lamin B2 origin of DNA replication. Journal of Biological Chemistry, 280(11), 9848-9854. PubMed
  14. Nikolic A, Divac A, Kusic J, Savic A. (2001) Frequency of the CFTR 2694T/G polymorphism and its association with CFTR-related monosymptomatic disorders Balkan J Med Genet; 4(1&2): 43-46
  15. Radojkovic D, Kusic J. (2000). Silver staining of denaturing gradient gel electrophoresis gels. Clinical Chemistry, 46(6), 883-884. PubMed
  16. Dork T … Kusic J, Radojkovic D … et al. (2000) Characterization of a novel 21-kb deletion, CFTRdele2,3(21 kb), in the CFTR gene: a cystic fibrosis mutation of Slavic origin common in Central and East Europe. Hum Genet 106(3): 259-268
  17. Kusic J, Radojkovic D, Cuppens H, Jaspers M, Tomic J, Savic A. (1999). Identification of a novel mutation (525del T) in exon 4 of the CFTR gene in a patient with cystic fibrosis. Human Mutation, 14(4), 357. PubMed

Edited books:

DNA Replication and Related Cellular Processes, edited by Jelena Kusic-Tisma, ISBN 978-953-307-775-8, Publisher: InTech, 2011. DOI: 10.5772/818

Fundamental Aspects of DNA Replication, edited by Jelena Kusic-Tisma, ISBN 978-953-307-259-3, Publisher: InTech, 2011. DOI: 10.5772/766

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