Aleksandra Nikolić

Viši naučni saradnik
Laboratorija za molekularnu biologiju (LMB)

Institut za molekularnu genetiku i genetičko inženjerstvo (IMGGI)
Univerzitet u Beogradu

Vojvode Stepe 444a, 11042 Beograd 152, Srbija
Mob:   +381 64 397 66 58
Tel:     +381 11 397 66 58
Fax:    +381 11 397 58 08
E-mail: aleksni@imgge.bg.ac.rs                                   

OBRAZOVANJE

2010 - Doktor bioloških nauka, Biološki fakultet (BF), Univerzitet u Beogradu (UB),
Strukturna i funkcionalna analiza 5’ regulatornog regiona gena SMAD4 u karcinomu pankreasa čoveka
2002 - Magistar bioloških nauka, BF, UB
2000 - Diplomirani molekularni biolog i fiziolog, BF, UB

ISTRAŽIVAČKO ISKUSTVO

2016 - viši naučni saradnik, IMGGE, UB
2010 - 2016
- naučni saradnik, IMGGI, UB
2002 - 2010 - istraživač saradnik, IMGGI, UB
2000 - 2002 - stipendista MNTRS

RADNO ISKUSTVO

2000 - Laboratorija za molekularnu biologiju, IMGGI, UB

OSTALE AKTIVNOSTI           

od 2010 - rukovodilac Programa biologije i hemije za srednjoškolce IMGGI
od 2015 - Predsednik Naučnog odbora Belgrade International Molecular Life Science Conference for Students
od 2017 - predavač na predmetu Akademske veštine na doktorskim studijama Biološkog fakulteta UB
od 2018 - Science Communication Manager COST akcije CA17118 TRANSCOLONCAN
2015-2016 - Član Progamskog saveta Centra za promociju nauke
2014 - Predsednik Organizacionog odbora Državnog prvenstva istraživačkih radova učenika srednjih škola
2014 - Potpredsednik Organizacionog odbora International Conference for Young Scientists
2012-2013 - Koordinator projekta Noć istraživača pod pokroviteljstvom Evropske unije

OBLAST NAUČNOG INTERESOVANJA

Molekularna osnova i farmakogenetika malignih gastrointestinalnih bolesti
Signalni put transformišućeg faktora rasta beta (TGFB)
Genetički faktori rizika u gastrointestinalnim i plućnim bolestima
Razvoj metoda za neinvazivnu molekularnu dijagnostiku

ODABRANI NAUČNI RADOVI

Jeremic I, Djuric O, Nikolic M, Vlajnic M, Nikolic A, Radojkovic D, Bonaci-Nikolic B. Neutrophil extracellular traps-associated markers are elevated in patients with systemic lupus erythematosus. Rheumatol Int 2019;39:1849–1857.

Nikolic A. Pathophysiology and genetics of bronchiectasis unrelated to cystic fibrosis. Lung. 2018;196(4):383-392.

Dragicevic S, Kosnik M, Divac Rankov A, Rijavec M, Milosevic K, Korosec P, Skerbinjek Kavalar M, Nikolic A. The polymorphisms in the 3' untranslated region of the matrix metalloproteinase 9 gene as modulators of asthma phenotype and treatment outcome. Lung 2018;196(3):297-303.

Supic G, Zeljic K, Divac Rankov A, Kozomara R, Nikolic A, Radojkovic D, Magic Z. miR-183 and miR-21 expression as biomarkers of progression and survival in tongue carcinoma patients. Clin Oral Investig 2018; 22(1): 401-409.

Dragicevic S, Milosevic M, Nestorovic B, Nikolic A. Influence of the Polymorphism C-509T in the TGFB1 Gene Promoter on the Response to Montelukast. Pediatr Aller Imm Pul. 2017;30(4):239-245.

Nikolic A, Vlajnic M, Ristanovic M, Petrovic J, Dimitrijevic I, Krivokapic Z, Radojkovic D. Cell-free DNA as biomarker and source for mutation detection in primary colorectal cancer. J BUON. 2017; 22(1): 178-183.

Vancevska A, Nikolic A, Bonaci-Nikolic B, Skiljevic D, Radojkovic D. Assessment of deoxyribonuclease activity in serum samples of patients with systemic lupus erythematosus: Fluorescence based method vs. ELISA. J Clin Lab Anal. 2016; 30(6): 797-803.

Nikolic A, Ristanovic M, Zivaljevic V, Rankov AD, Radojkovic D, Paunovic I. SMAD4 gene promoter mutations in patients with thyroid tumors. Exp Mol Pathol. 2015; 99(1): 100-103.

Nikolic A, Cacev T, Aralica G, Popovic Hadzija M, Kapitanovic S, Radojkovic D. Mononucleotide repeats in the SMAD4 gene promoter in colon carcinoma tissue of Croatian patients. Exp Mol Pathol. 2015; 98(2): 133-135.

Nikolic A, Milosevic K, Boskovic S, Nestorovic B. Neutrophil Elastase Gene Polymorphisms: Modulators of Response to Therapy in Childhood Bronchiectasis? Lung. 2014; 192(4): 595-599.

Vancevska A, Nikolic A. Method for assessment of deoxyribonuclease activity in biological samples. Lab Medicine 2013; 44(2): 125-128

Nikolic A, Ristanovic M, Perovic V, Trifunovic J, Perovic M, Radojkovic D. Genetic Alterations in SMAD4 and K-ras in Serbian Patients With Endometrial Carcinoma. Int J Gynecol Cancer. 2012; 22(3): 442-446.

Nikolic A, Kojic S, Knezevic S, Krivokapic Z, Ristanovic M, Radojkovic D. Structural and functional analysis of SMAD4 gene promoter in malignant pancreatic and colorectal tissues: detection of two novel polymorphic nucleotide repeats. Cancer Epidemiol 2011; 35(3): 265-271.

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