Aleksandra Divac Rankov

Viši naučni saradnik
Laboratorija za molekularnu biologiju (LMB)

Institut za molekularnu genetiku i genetičko inženjerstvo (IMGGI),
Univerzitet u Beogradu (UB)

V. Stepe 444a, P. fah 23, 11010 Beograd, Srbija
Mob: +381 65 397 66 58
Tel:   +381 11 397 66 58
Fax:  +381 11 397 58 08
E-mail: aleksandradivac@imgge.bg.ac.rs

OBRAZOVANJE

2008 - Doktor bioloških nauka, Biološki fakultet (BF), UB, (Teza: „Promene strukture DNK izazvane proteinom HsOrc4“)
2003 - Magistar bioloških nauka, BF, UB
2001 - Diplomirani biolog, BF, UB

ISTRAŽIVAČKO ISKUSTVO

2018 - viši naučn saradnik, IMGGI, UB
2008
- 2018 - naučni saradnik, IMGGI, UB
2002 - 2008 - istraživač saradnik, IMGGI, UB
2001 - 2002 - stipendista MNTRS

OSTALE AKTIVNOSTI

Postdoktorsko usavršavanje (2016-17) u Departmanu za genetiku, Eotvoš Lorand Univerziteta, Budipmešta, Mađarska – Zebrica (Danio rerio) kao model sistem za ispitivanje efekata nikotina kroz generacije

3. mesto na takmičenju Najbolja tehnološka inovacija Srbije (2008), predlog „Combined analysis of molecular markers CA19-9 i K-RAS G12 in diagnostics of pancreatic carcinoma“

Young Scientist Award na First Eastern European CF Conference:”What’s New in the Diagnosis, Treatment and Prevention of Cystic Fibrosis?”, (2008), Zagreb, Hrvatska

Nagrada za najbolji doktorski rad iz oblasti molekularne biologije (2008) Fondacije Goran Ljubijankić

OBLAST NAUČNOG INTERESOVANJA

Biomarkeri u bolestima čoveka (plućne bolesti i solidni tumori), molekularna osnova, genetski i epigentiski faktori rizika za razvoj plućnih bolesti, zebrica (Danio rerio) kao model sistem za izučavanje hroničnih bolesti čoveka, toksikološke studije na model sistemu zebrice (Danio rerio)

ODABRANI NAUČNI RADOVI

Hammer B, Wagner C, Divac Rankov A, Reuter S, Bartel S, Hylkema MN, Krüger A, Svanes C, Krauss-Etschmann S. In utero exposure to cigarette smoke and effects across generations: A conference of animals on asthma. Clin Exp Allergy. 2018. 48(11):1378-1390. [PubMed]

Divac Rankov A, Ljujić M, Petrić M, Radojković D, Pešić M, Dinić J. Targeting autophagy to modulate cell survival: a comparative analysis in cancer, normal and embryonic cells. Histochem Cell Biol. 2017. 148(5):529-544. [PubMed]

Dragicevic S, Kosnik M, Divac Rankov A, Rijavec M, Milosevic K, Korosec P, Skerbinjek Kavalar M, Nikolic A. The Variants in the 3' Untranslated Region of the Matrix Metalloproteinase 9 Gene as Modulators of Treatment Outcome in Children with Asthma. Lung. 2018 Jun;196(3):297-303. [PubMed]

Nestorović-Živković J, Živković S, Šiler B, Aničić N, Dmitrović S, Divac Rankov A, Giba Z, Mišić D. Differences in bioactivity of three endemic Nepeta species arising from main terpenoid and phenolic constituents. Arch Biol Sci. 2018;70(1):63-76.

Supic G, Zeljic K, Divac Rankov A, Kozomara R, Nikolic A, Radojkovic D, Magic Z. miR-183 and miR-21 expression as biomarkers of progression and survival in tongue carcinoma patients. Clin Oral Investig. 2018 Jan;22(1):401-409. [PubMed]

Nikolic A, Ristanovic M, Zivaljevic V, Divac Rankov A, Radojkovic D, Paunovic I. SMAD4 gene promoter mutations in patients with thyroid tumors. Exp Mol Pathol. 2015 Aug;99(1):100-3. [PubMed]

Ljujic M, Divac Rankov A, Kojic S, Miranda E, Radojkovic D. (2014) Functional analysis of novel alpha-1 antitrypsin variants G320R and V321F. Mol Biol Rep, 41(9):6133-41. [PubMed]

Milosevic K, Nikolic A, Divac Rankov A, Ljujic M, Nestorovic B, Radojkovic D. (2013) Analysis of CFTR Gene Variants in Idiopathic Bronchiectasis in Serbian Children. Pediatr Allergy Immunol Pulmonol, 26(2):93-98. [PubMed]

Topic A, Stankovic M, Divac-Rankov A, Petrovic-Stanojevic N, Mitic-Milikic M, Nagorni-Obradovic L, Radojkovic D. (2012) Alpha-1-antitrypsin deficiency in Serbian adults with lung diseases. Genet Test Mol Biomarkers, 16(11):1282-6. [PubMed]

Kojic S, Nestorovic A, Rakicevic L, Belgrano A, Stankovic M, Divac A, Faulkner G.  (2010) A novel role for cardiac ankyrin repeat protein Ankrd1/CARP as a co-activator of the p53 tumor suppressor protein. Arch Biochem Biophys, 502(1):60-7. [PubMed]

Ljujic M, Topic A, Nikolic A, Divac A, Grujic M, Mitic-Milikic M, Radojkovic D (2010) Identification of a rare p.G320R alpha-1-antitrypsin variant in emphysema and lung cancer patients. Genet Mol Bio, 33(1): 5-8.[PubMed]

Divac A, Tomić B, Kušić J (2010) The role of adenosine triphosphate in the function of human origin recognition complex 4 protein. J Serb Chem Soc. 75(3): 317–22.

Kusic J, Tomic B, Divac A, Kojic S. (2010) Human initiation protein Orc4 prefers triple stranded DNA. Mol Biol Rep, 37(5):2317-22. [PubMed]

Radojkovic M, Ristic S, Divac A, Tomic B, Nestorovic A, Radojkovic D. (2009) Novel ORC4L gene mutation in B-cell lymphoproliferative disorders. Am J Med Sci, 338(6):527-9. [PubMed]

Stankovic M, Nikolic A, Divac A, Rakicevic L, Tomovic A, Mitic-Milikic M, Nagorni-Obradovic L, Grujic M, Petrovic-Stanojevic N, Andjelic-Jelic M, Dopudja-Pantic V, Radojkovic D. (2009) Matrix metalloproteinases gene variants in idiopathic disseminated bronchiectasis. J Investig Med, 57(3):500-3. [PubMed]

Stanković M, Nikolic A, Divac A, Tomovic A, Petrovic-Stanojevic N, Andjelic M, Dopudja-Pantic V, Surlan M, Vujicic I, Ponomarev D, Mitic-Milikic M, Kusic J, Radojkovic D. (2008) The CFTR M470V gene variant as a potential modifier of COPD severity – study of serbian population. Genet Test, 12(3):357-62. [PubMed]

Stefanovic D, Kusic J, Divac A, Tomic B. (2008) Formation of noncanonical DNA structures mediated by human ORC4, a protein component of origin recognition complex, Biochemistry, 47(33):8760-7. [PubMed]

Ljujic M, Topic A, Divac A, Nikolic A, Petrovic-Stanojevic N, Surlan M, Mitic-Milikic M, Radojkovic D. (2008) Isoelectric focusing phenotyping and denaturing gradient gel electrophoresis genotyping: a comparison of two methods in detection of alpha-1-antitrypsin variants, Transl Res, 151(5):255-9. [PubMed]

Ljujic M, Nikolic A, Divac A, Djordjevic V, Radojkovic D. (2006) Screening of alpha-1-antitrypsin gene by denaturing gradient gel electrophoresis (DGGE). J Biochem Biophys Methods, 68(3):167-73. [PubMed]

Divac A, Nikolic A, Mitic-Milikic M, Nagorni-Obradovic L, Petrovic-Stanojevic N, Dopudja-Pantic V, Nadaskic R, Savic A, Radojkovic D. (2005) CFTR mutations and polymorphisms in adults with disseminated bronchiectasis: a controversial issue. Thorax, 60(1):85. [PubMed]

Kusic J, Kojic S, Divac A, Stefanovic D. (2005) Noncanonical DNA elements in the lamin B2 origin of DNA replication. J Biol Chem, 280(11):9848-54. [PubMed]

Divac A, Nikolic A, Mitic-Milikic M, Nagorni-Obradovic L, Petrovic-Stanojevic N, Dopudja-Pantic V, Nadaskic R, Savic A, Radojkovic D. (2004) High frequency of the R75Q CFTR variation in patients with chronic obstructive pulmonary disease. J Cyst Fibros. 3(3):189-91. [PubMed]

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