Detection of numerical chromosome aberrations and microdeletions by fluorescent in situ hybridization

Fluorescent in situ hybridization (FISH) is employed for detection of numerical aberrations of chromosomes 1, 13, 18, 21, X i Y and microdeletions 22q11.2 and 15q11 in Laboratory for Human Molecular Genetics. FISH is a molecular cytogenetic technique that is based on the hybridization between specific, fluorescently labeled DNA probe and complementary sequence in the biological sample, followed by the detection of the formed hybrid using fluorescence microscopy.

Only samples with filled request form from the medical doctor are accepted.

Contact:

Danijela Drakulic, PhD
Laboratory for Human Molecular Genetics

tel. +381 11 3976 212
fax. +381 11 3975 808
email: danijeladrakulic@imgge.bg.ac.rs

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