Detection of numerical aberrations of chromosomes X, Y, 13, 18 and 21 in the spermatozoa by using FISH methods

FISH- Fluorescent in situ hybridization is a molecular cytogenetic technique which gives the information about the genetic content of the cell. By applying the FISH method we can evaluate whether there is an increased risk for embryo’s chromosomal abnormality originated from sperm. This method gives precise information about chromosome 13, 18, 21, X and Y aneuploidies present in sperm cells. The analysis is conducted on microscope preparations prepared from fresh sperm sample delivered to the laboratory within 1h after ejaculation.    

The analysis is also available for frozen sperm samples by prior arrangement with the hospital which offer sperm freezing.


The samples are accepted only with prior scheduling.

Contact: Jelena Popovic, PhD

Laboratory for Human Molecular Genetics

tel. +381 11 3976 212; fax. +381 11 3975 808

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