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INSTITUTE OF MOLECULAR GENETICS
AND GENETIC ENGINEERING
University of Belgrade

Detection of numerical aberrations of chromosomes X, Y, 13, 18 and 21 in the spermatozoa by using FISH methods

This analysis gives precise information about sperm aneuploidy rate for chromosomes 13, 18, 21, X and Y. Studies shown that an elevated sperm aneuploidy rate is associated with a lower rate of pregnancy and higher rate of spontaneous abortions. The method employed for this analysis is fluorescent in situ hybridization (FISH). FISH is a molecular cytogenetic technique based on the hybridization between specific, fluorescently labeled DNA probe and complementary sequence in the biological sample.

For analysis is necessary fresh sperm sample delivered to the laboratory within 1h after ejaculation.

The analysis is also available for frozen sperm samples by prior arrangement with hospital that offers sperm freezing.

The samples are accepted only with prior scheduling.

 

Contact: 

Danijela Drakulic, PhD

Laboratory for Human Molecular Genetics

tel. +381 11 3976 212

fax. +381 11 3975 808

email: danijeladrakulic@imgge.bg.ac.rs

Head office / Mailing address: Vojvode Stepe 444a, 11042 Belgrade 152, Serbia / Web System By Emarket1ng.NET