Group for Gene Regulation in Cancer studies the structure and function of regulatory DNA and RNA elements and their role in the development and progression of malignant diseases.
The main research topics are:
The research is focused on solid tumors of the gastrointestinal tract: colorectal cancer, pancreatic cancer, hepatocellular cancer and oral cancer. The research also includes lung cancer, thyroid cancer and ovarian cancer.
Research is performed on 2D and 3D cell cultures and tumor and non-tumor tissue samples obtained during tumor resection or biopsy. Special attention is dedicated to the development of a model system for ex vivo stimulation of tumor tissue in order to examine the mechanisms and determinants of the response to chemoradiotherapy.
In addition to classical techniques of molecular and cell biology, the research is conducted using modern bioinformatics approaches and high-throughput methods - transcriptomics and proteomics.
Students of all levels of study are involved in the work through the realization of seminar and scientific research papers.
Innovation activities are aimed at examining the potential of regulatory DNA and RNA elements as biosensors, biomarkers and therapeutic targets in cancer.
Vojvode Stepe 444a
P.O BOX 23
11010 Beograd, Srbija
Tel: +381 11 3976658
Mob: +381 66 8038498
Faks: +381 11 3975808