Naučni savetnik
Laboratorija za molekularnu biologiju biljaka

Institut za molekularnu genetiku i genetičko inženjerstvo (IMGGI),
Univerzitet u Beogradu,

V. Stepe 444a, 11010 Beograd, Srbija
Mob:   +381 65 397 64 14
Tel:     +381 11 397 64 14
Fax:    +381 11 397 58 08
E-mail: mdkojic@imgge.bg.ac.rs

OBRAZOVANJE

1994 - doktor bioloških nauka, Biološki fakultet (BF), Univerzitet u Beogradu (UB),
(ANALIZA REGULATORNIH REGIONA I EKSPRESIJA sgm GENA BAKTERIJE Micromospora zionensis)
1992 - magistar bioloških nauka, BF, UB
1987 - diplomirani biolog, BF, UB

ISTRAŽIVAČKO ISKUSTVO

2012 - naučni savetnik, IMGGI, UB
1997 - 2012 - Kornel, SAD
1994 - 1997 - naučni saradnik, IMGGI, UB
1992 - 1994 - istraživač saradnik, IMGGI, UB
1989 - 1992 - istraživač, IMGGI, UB
1988 - 1989 - istraživač pripravnik, Institut za molekularnu genetiku i genetičko inženjerstvo, (IMGGI), UB

OBLAST NAUČNOG INTERESOVANJA

Molekularna genetika, razvoj novih selektivnih markera i plazmidnih vektora, očuvanje igenetičkog ntegriteta, reparacija DNK, homologna rekombinacija, resolucija rekombinacionih intermedijera, mejoza, odbrana od oksidativnog napada

ODABRANI NAUČNI RADOVI 

Bautista-España D, Anastacio-Marcelino E, Horta-Valerdi G, Celestino-Montes A, Kojic M, Negrete-Abascal E, Reyes-Cervantes H, Vázquez-Cruz C, Guzmán P, Sánchez-Alonso P. The Telomerase Reverse Transcriptase Subunit from the Dimorphic Fungus Ustilago maydis. PLoS One. 2014 Oct 9;9(10):e109981. doi: 10.1371/journal.pone.0109981. eCollection 2014.  http://www.ncbi.nlm.nih.gov/pubmed/25299159

Kojic M, Sutherland JH, Pérez-Martín J, Holloman WK. Initiation of Meiotic Recombination in Ustilago maydis. Genetics. 2013 Dec;195(4):1231-40. doi: 10.1534/genetics.113.156752. Epub 2013 Sep 27. http://www.ncbi.nlm.nih.gov/pubmed/24077302

Yu EY, Kojic M, Holloman WK, Lue NF. Brh2 and Rad51 promote telomere maintenance in Ustilago maydis, a new model system of DNA repair proteins at telomeres. DNA Repair (Amst). 2013 Jul; 12(7):472-9. doi: 10.1016/j.dnarep.2013.04.027. Epub 2013 May 28.http://www.ncbi.nlm.nih.gov/pubmed/23726221

Zhou Q, Kojic M, Holloman WK. Dss1 Release Activates DNA Binding Potential in Brh2. Biochemistry. 2012 Nov 13; 51(45):9137-46. doi: 10.1021/bi3011187. Epub 2012 Nov 2. http://www.ncbi.nlm.nih.gov/pubmed/23094644

Kojic M, Holloman WK. Brh2 domain function distinguished by differential cellular responses to DNA damage and replication stress. Mol Microbiol. 2012 Jan; 83(2): 351-61. doi: 10.1111/j.1365-2958.2011.07935.x. Epub 2011 Dec 15. http://www.ncbi.nlm.nih.gov/pubmed/22171788

Kojic M, Zhou Q, Fan J, Holloman WK. Mutational analysis of Brh2 reveals requirements for compensating mediator functions. Mol Microbiol. 2011 Jan;79(1):180-91. doi: 10.1111/j.1365-2958.2010.07440.x. Epub 2010 Nov 2. http://www.ncbi.nlm.nih.gov/pubmed/21166902

Zhou Q, Mazloum N, Mao N, Kojic M, Holloman WK. Dss1 regulates interaction of Brh2 with DNA.Biochemistry. 2009 Dec 22; 48(50):11929-38. http://www.ncbi.nlm.nih.gov/pubmed/19919104

Mao N, Kojic M, Holloman WK. Role of Blm and collaborating factors in recombination and survival following replication stress in Ustilago maydis. DNA Repair (Amst). 2009 Jun 4;8(6): 752-9. Epub 2009 Apr 5. http://www.ncbi.nlm.nih.gov/pubmed/19349216

Zhou Q, Kojic M, Holloman WK. DNA-binding Domain within the Brh2 N Terminus is the Primary Interaction Site for Association with DNA.J Biol Chem. 2009 Mar 27; 284(13):8265-73. Epub 2009 Feb 1. http://www.ncbi.nlm.nih.gov/pubmed/19182269

11) Kojic M, Mao N, Zhou Q, Lisby M, Holloman WK.Compensatory role for Rad52 during recombinational repair in Ustilago maydis. Mol Microbiol. 2008 Feb 3;67(5):1156-1168. Epub 2008 Jan 15 http://www.ncbi.nlm.nih.gov/pubmed/18208529.

Mao N, Zhou Q, Kojic M, Perez-Martin J, Holloman WK. Ortholog of BRCA2-interacting protein BCCIP controls morphogenetic responses during DNA replication stress in Ustilago maydis. DNA Repair (Amst). 2007 Nov; 6(11):1651-60. Epub 2007 Jul 12. http://www.ncbi.nlm.nih.gov/pubmed/17627904

Zhou Q, Kojic M, Cao Z, Lisby M, Mazloum NA, Holloman WK. Dss1 interaction with Brh2 as a regulatory mechanism for recombinational repair. Mol Cell Biol. 2007 Apr; 27(7):2512-26. Epub 2007 Jan 29. http://www.ncbi.nlm.nih.gov/pubmed/17261595

Kojic M, Zhou Q, Lisby M, Holloman WK. Rec2 Interplay with both Brh2 and Rad51 Balances Recombinational Repair in Ustilago maydis. Mol Cell Biol. 2006 Jan;26(2):678-88. http://www.ncbi.nlm.nih.gov/pubmed/16382157

Kojic M, Zhou Q, Lisby M, Holloman WK. Brh2-Dss1 Interplay Enables Properly Controlled Recombination in Ustilago maydis. Mol Cell Biol. 2005 Apr;25(7):2547-57. http://www.ncbi.nlm.nih.gov/pubmed/15767662

Kojic M, Holloman WK. BRCA2-RAD51-DSS1 Interplay Examined from a Microbial Perspective. Cell Cycle. 2004 Mar; 3(3):247-248. http://www.ncbi.nlm.nih.gov/pubmed/14726651

Kojic M, Yang HJ, Kostrub CF, Pavletich NP, Holloman WK. The BRCA2    interacting protein DSS1 is vital for DNA repair, recombination, and genome stability in Ustilago maydis. MOLECULAR CELL 12 (4): 1043-1049 OCT 2003. http://www.ncbi.nlm.nih.gov/pubmed/14580353

Kojic, M.,  Corwin F. Kostrub, Andrew R. Buchman, and William K. Holloman (2002) BRCA2 Homolog Required for Proficiency in DNA Repair, Recombination, and Genome Stability in Ustilago maydis . Molecular Cell, Vol. 10, 683–691. http://www.ncbi.nlm.nih.gov/pubmed/12408834

Kojic, M., Thompson, C. W. and Holloman, W. K. (2001) Disruptions of the Ustilago maydis REC2 gene identify a protein domain important in directing recombinational repair of DNA.  Mol. Microbiol. 40 (6), 1415-1426. http://www.ncbi.nlm.nih.gov/pubmed/11442839

Kojic, M. and Holloman, W.K. (2000) Shuttle vectors for genetic manipulations in Ustilago maydis. Can. J. Microbiol. 46, 333-338. http://www.ncbi.nlm.nih.gov/pubmed/10779869 

Kojic, M., Milojevic, N., Vasiljevic, B. (1999) Gentamicin-resistance determinants confer background-dependent hygromycin B resistance. Microbial Drug Resistance, 5, 177-182. http://www.ncbi.nlm.nih.gov/pubmed/10566866