Naučni saradnik
Laboratorija za humanu molekularnu genetiku

Institut za molekularnu genetiku i genetičko inženjerstvo (IMGGI),
Univerzitet u Beogradu,

V. Stepe 444a, 11010 Beograd, Srbija
Mob: +381 65 3976212
Tel:   +381 11 3976212
Fax:  +381 11 397 58 08
E-mail: schwirtlich@imgge.bg.ac.rs                                   

OBRAZOVANJE

2009 - Doktor medicinskih nauka, smer funcionalne neuroanatomija, Semelvajs Univerzitet, Budimpešta, Republika Madjarska.
Diploma je 2012 nostrifikovana kao diploma doktora bioloških nauka, Biološki fakultet (BF), Univerzitet u Beogradu (UB),
(Naslov teme: Molekularne komponente i funkcija GABA signalizacije tokom razvića )
1998 - Diplomirani biolog, BF, UB

ISTRAŽIVAČKO ISKUSTVO

2012 - naučni saradnik, Institut za molekularnu genetiku i genetičko inženjerstvo, (IMGGI), UB, UB

RADNO ISKUSTVO

2012 - istraživač u  Laboratoriji za humanu molekularnu genetiku,  Instituta   za molekularnu genetiku i genetičko inženjerstvo, (IMGGI), UB,
2001 – 2010 - istraživač u Institutu za eksperimentalnu medicinu Madjarske Akademije Nauka, Budimpešta, Republika Madjarska
1998 - 2001 - istraživač na Odeljenju za neurobiologiju, Biološkog instituta Siniša Stanković, UB           

OSTALE AKTIVNOSTI

2012 - član Društva za neuronauke Srbije

OBLAST NAUČNOG INTERESOVANJA

Proučavanje funkcije SOXB1( SOX1, SOX2, SOX3) i SOXB2 (SOX14  i SOX21) članova SOXB familije transkripcionih faktora u regulaciji proliferacije embrionalnih i karcinomskih matičnih ćelija kao i diferencijaciji neuralnih progenitora tokom razvića nervnog sistema.

ODABRANI NAUČNI RADOVI

In press:

Drakulic D, Marjanovic Vicentic J, Schwirtlich M, Tosic J, Krstic A, Klajn A, Stevanovic M. The overexpression of SOX2 affects the migration of human
teratocarcinoma cell line NT2/D1. An. Acad. Bras. Ciênc., 2014

Klajn A, Drakulic D, Tosic M, Pavkovic Z, Schwirtlich M, Stevanovic M. Effects of constitutive SOX2 overexpression on neural differentiation of
NT2/D1 cells. Biochemistry (Moscow), 2014

Published:

Mojsin M, Vicentic JM, Schwirtlich M, Topalovic V, Stevanovic M. Quercetin reduces pluripotency, migration and adhesion of human teratocarcinoma cell line NT2/D1 by inhibiting Wnt/β-catenin signaling. Food Funct. 2014 Oct 24;5(10):2564-73.  http://www.ncbi.nlm.nih.gov/pubmed/25138740

Vastagh C, Schwirtlich M, Kwakowsky A, Erdélyi F, Margolis FL, Yanagawa Y, Katarova Z, Szabó G. The spatio-temporal segregation of GAD forms defines distinct GABA signaling functions in the developing mouse olfactory system and provides novel insights into the origin and migration of GnRH neurons. Dev Neurobiol. 2014 Aug 14. http://www.ncbi.nlm.nih.gov/pubmed/25125027

Popovic J, Stanisavljevic D, Schwirtlich M, Klajn A, Marjanovic J, Stevanovic M. Expression analysis of SOX14 during retinoic acid induced neural differentiation of embryonal carcinoma cells and assessment of the effect of its ectopic expression on SOXB members in HeLa cells.PLoS One. 2014 Mar 17;9(3):e91852. http://www.ncbi.nlm.nih.gov/pubmed/24637840

Schwirtlich M, Kwakowsky A, Emri Z, Antal K, Lacza Z, Cselenyák A, Katarova Z, Szabó G. GABAergic signaling in primary lens epithelial and lentoid cells and its involvement in intracellular Ca2+ modulation.Cell Calcium. 2011 Oct;50(4):381-92. http://www.ncbi.nlm.nih.gov/pubmed/21820173

Schwirtlich M, Emri Z, Antal K, Máté Z, Katarova Z, Szabó G. GABA(A) and GABA(B) receptors of distinct properties affect oppositely the proliferation of mouse embryonic stem cells through synergistic elevation of intracellular Ca(2+).FASEB J. 2010 Apr;24(4):1218-28. http://www.ncbi.nlm.nih.gov/pubmed/19959723

Kwakowsky A, Schwirtlich M, Kooy F, Abrahám I, Máté Z, Katarova Z, Szabó G. GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality.Dev Dyn. 2008 Dec;237(12):3830-41. http://www.ncbi.nlm.nih.gov/pubmed/18985723

Kwakowsky A, Schwirtlich M, Zhang Q, Eisenstat DD, Erdélyi F, Baranyi M, Katarova ZD, Szabó G. GAD isoforms exhibit distinct spatiotemporal expression patterns in the developing mouse lens: correlation with Dlx2 and Dlx5.Dev Dyn. 2007 Dec;236(12):3532-44.  http://www.ncbi.nlm.nih.gov/pubmed/17969168