Naučni savetnik
Laboratorija za molekularnu genetiku i ekologiju mikroorganizama (LMGEM)

Institut za molekularnu genetiku i genetičko inženjerstvo (IMGGI),
Univerzitet u Beogradu,

Vojvode Stepe 444a, P. Fah 23, 11010 Beograd, Srbija
Mobile:  +381 65 397 60 34
Phone:  +381 11 397 60 34
Fax:      +381 11 397 58 08
E-mail: jasmina.nikodinovic@imgge.bg.ac.rs

OBRAZOVANJE

2004 - Doktor molekularne genetike i biohemije, Univerzitet Novog Južnog Velsa, Sidnej, Australija (www.unsw.edu.au)
(Teza: Molecular genetics of amphotericin biosynthesis in Streptomyces nodosus)
2000 - B.Sc. Molekularna genetika, Univerzitet Zapadnog Sidneja, Sidnej, Australija (www.uws.edu.au)

RADNO ISKUSTVO

2014 - Naučni savetnik,Laboratorija za molekularnu genetiku i ekologiju mikroorganizama, IMGGI
2011 - 2014 -Viši naučni saradnik, Laboratorija za molekularnu genetiku i ekologiju mikroorganizama, IMGGI
2006 - 2010 - Viši naučnik istraživač, Grupa za Biokatalizu, UCD, Dablin, Irska (www.ucd.ie)
2004 - 2006 - Postdoktorand, Katedra za hemiju, Univerzitet u Montani, Misula, MT, USA (www.cas.umt.edu)

TEKUĆE SARADNJE

Dr Kevin O’Connor - University College Dublin, Ireland (www.ucd.ie)
Prof Nigel D Priestley – University of Montana, MT, USA (www.umt.edu)
Prof Evangelos Topakas - National Technical University of Athens, Athens, Greece (www.ntua.gr)
Prof Tobias Gulder – Technical University of Munich, Germany (www.tum.de)
Prof Miloš Đuran - Institut za hemiju, Prirodno-matematički fakultet, Univerzitet u Kragujevcu, Srbija (www.kg.ac.rs)
Dr Igor Opsenica – Hemijski fakultet, Univerzitet u Beogradu, Srbija (www.chem.bg.ac.rs)
Dr Veselin Maslak – Hemijski fakultet, Univerzitet u Beogradu, Srbija (www.chem.bg.ac.rs)
Prof Vladimir Savić – Farmaceutski fakultet, Univerzitet u Beogradu, Srbija (www.pharmacy.bg.ac.rs)
Dr Radivoje Prodanović – Hemijski fakultet, Univerzitet u Beogradu, Srbija (www.chem.bg.ac.rs)
Prof Niko Radulović – Prirodno-matematicki fakultet, University u Nisu, Srbija (www.pmf.ni.ac.rs/pmf)
Dr Melina Kalagasidis Krušić – Tehnolosko-metalurski fakultet, Univerzitet u Beogradu, Srbija (www.tmf.bg.ac.rs)

OBLAST NAUČNOG INTERESOVANJA

BIOTEHNOLOGIJA (bakterijske fermentacije, poboljsanje bakterijskih sojeva primenom tradicionalnih i molekularnih metoda, Streptomyces spp., Pseudomonas spp.);
BIOKATALIZA (ekspresija i dirigovana evolucija proteina, tautomeraze, lakaze, aminotransferaze, biotransformacije, razvoj i optimizacija biokatalitickih procesa);
NOVI MATERIJALI (biopolimeri, polihidroksialkanoati, funkcionalizacija biopolimera);
SEKUNDARNI METABOLITI I BIOAKTIVNA JEDINJENJA IZ BAKTERIJA (biopigmenti, antigljivična i antitumorska jedinjenja)

ODABRANI NAUČNI RADOVI

Bioaktivni molekuli

Warżajtis B, Glišić BĐ, Savić ND, Pavic A, Vojnovic S, Veselinović A, Nikodinovic-Runic J, Rychlewska U, Djuran MI. Mononuclear gold(III) complexes with L-histidine-containing dipeptides: tuning the structural and biological properties by variation of the N-terminal amino acid and counter anion. J Inorg Biochem. (2017); (174): 156-68. https://www.ncbi.nlm.nih.gov/pubmed/28675847

Radivojevic J, Skaro S, Senerovic L, Vasiljevic B, Guzik M, Kenny ST, Maslak V, O'Connor KE, Nikodinovic-Runic J. Polyhydroxyalkanoate-based 3-hydroxyoctanoic acid and its derivatives as a platform of bioactive compounds. Appl Microbiol Biotechnol. (2016); 100(1):161-72. http://www.ncbi.nlm.nih.gov/pubmed/26399414

Ajdačić V, Senerovic L, Vranić M, Pekmezovic M, Arsic-Arsnijevic V, Veselinovic A, Veselinovic J, Šolaja BA, Nikodinovic-Runic J, Opsenica IM. Synthesis and evaluation of thiophene-based guanylhydrazones (iminoguanidines) efficient against panel of voriconazole-resistant fungal isolates. Bioorg. Med. Chem. (2016); 24(6): 1277–91. http://www.ncbi.nlm.nih.gov/pubmed/26867487

Simic M, Paunovic N, Boric I, Randjelovic J, Vojnovic S, Nikodinovic-Runic J, Pekmezovic M, Savic V. Functionalised isocoumarins as antifungal compounds: Synthesis and biological studies. Bioorg. Med. Chem. Lett. (2016); 26(1):235-9. http://www.ncbi.nlm.nih.gov/pubmed/26586600

Glišić BĐ, Senerovic L, Comba P, Wadepohl H, Veselinovic A, Milivojevic DR, Djuran MI, Nikodinovic-Runic J. Silver(I) complexes with phthalazine and quinazoline as effective agents against pathogenic Pseudomonas aeruginosa strains. J. Inorg. Biochem. (2016); 155:115-28. http://www.ncbi.nlm.nih.gov/pubmed/26687023

Senerovic L, Zivkovic MD, Veselinovic A, Pavic A, Djuran MI, Rajkovic S, Nikodinovic-Runic J. Synthesis and evaluation of series of diazine-bridged dinuclear platinum(II) complexes through in vitro toxicity and molecular modeling: correlation between structure and activity of Pt(II) complexes. J. Med. Chem. (2015); 58(3):1442-51. http://www.ncbi.nlm.nih.gov/pubmed/25551180

Stankovic N, Senerovic L, Ilic-Tomic T, Vasiljevic B, Nikodinovic-Runic J. Properties and applications of undecylprodigiosin and other bacterial prodigiosins. Appl. Microbiol. Biotechnol. (2014); 98, 3841-58. http://www.ncbi.nlm.nih.gov/pubmed/24562326

Nikodinovic-Runic J, Mojic M, Kang Y, Maksimovic-Ivanic D, Mijatovic S, Vasiljevic B, Stamenkovic V, Senerovic L. Undecylprodigiosin conjugated monodisperse gold nanoparticles efficiently cause apoptosis in colon cancer cells in vitro. J. Mater. Chem. B (2014); 2, 3271 - 3281. http://pubs.rsc.org/en/Content/ArticleLanding/2014/TB/c4tb00300d#!divAbstract

Stankovic, N., Senerovic, L., Bojic-Trbojevic, Z., Vuckovic, I., Vicovac, Lj., Vasiljevic, B., Nikodinovic-Runic, J..Didehydroroflamycoin (DDHR) pentaene macrolide family from Streptomyces durmitorensis MS405T: Production optimization and antimicrobial activity. J. Appl. Microbiol. (2013); 115(6):1297-306. http://www.ncbi.nlm.nih.gov/pubmed/23941529

O'Connor, S., Szwej, E., Nikodinovic-Runic, J., O'Connor, A., Byrne, A.T., Devocelle, M., O'Donovan, N., Gallagher, W.M., Babu, R., Kenny, S.T., Zinn, M., Zulian, Q.R., O'Connor, K.E. The anti-cancer activity of a cationic anti-microbial peptide derived from monomers of polyhydroxyalkanoate. Biomaterials (2013); 34, 2710–18. http://www.ncbi.nlm.nih.gov/pubmed/23343631

Biokataliza i biopolimeri

Narancic T, Davis R, Nikodinovic-Runic J, O' Connor KE. Recent developments in biocatalysis beyond the laboratory. Biotechnol Lett. 2015; 37(5):943-54. http://www.ncbi.nlm.nih.gov/pubmed/25555685

Djokic L, Spasic J, Jeremic S, Vasiljevic B, Prodanovic O, Prodanovic R, Nikodinovic-Runic J. Immobilization of Escherichia coli cells expressing 4-oxalocrotonate tautomerase for improved biotransformation of β-nitrostyrene. Bioprocess Biosyst. Eng. (2015); 38(12):2389-95. http://www.ncbi.nlm.nih.gov/pubmed/26410191

Jovanovic P, Jeremic S, Djokic L, Savic V, Radivojevic J, Maslak V, Ivkovic B, Vasiljevic B, Nikodinovic-Runic J. Chemoselectivebiocatalytic reduction of conjugated nitroalkenes: New application for an Escherichia coli BL21(DE3) expression strain. Enz Microb Technol (2014); 60C, 16-23. http://www.ncbi.nlm.nih.gov/pubmed/24835095

Guzik MW, Kenny ST, Duane GF, Casey E, Woods T, Babu RP, Nikodinovic-Runic J, Murrey M, O’Connor K. Conversion of post consumer polyethylene to the biodegradable polymer polyhydroxyalkanoate. Appl. Microbiol. Biotechnol. (2014); 98, 4223-32. http://www.ncbi.nlm.nih.gov/pubmed/24413975

Molloy, S., Nikodinovic-Runic, J., Martin, L.B., Hartmann, H., Solano, F., Decker, H., O'Connor, K.E. Engineering of a bacterial tyrosinase for improved catalytic efficiency towards D-tyrosine using random and site directed mutagenesis approaches. Biotechnol. Bioeng. (2013); 110, 1849–57. http://www.ncbi.nlm.nih.gov/pubmed/23381872

Narancic, T., Radivojevic, J., Jovanovic, P., Francuski, D., Bigovic, M., Maslak, V., Savic, V., Vasiljevic, B., O'Connor, K.E., Nikodinovic-Runic, J. Highly efficient Michael-type addition of acetaldehyde to b-nitrostyrenes by whole resting cells of Escherichia coli expressing 4-oxalocrotonate tautomerase. Biores. Technol. (2013); 142, 462–68. http://www.ncbi.nlm.nih.gov/pubmed/23759430

Nikodinovic-Runic, J., Guzik, M., Kenny, S.T., Babu, R., Werker, A., O'Connor, K.E. Carbon-rich wastes as feedstocks for biodegradable polymer (polyhydroxyalkanoate) production using bacteria. Adv. Appl. Microbiol. (2013); 84, 139-200. http://www.ncbi.nlm.nih.gov/pubmed/23763760

Narancic, T., Djokic, L., Kenny, S.T., O'Connor, K.E., Radulovic, V., Nikodinovic-Runic, J., Vasiljevic, B. Metabolic versatility of Gram-positive microbial isolates from contaminated river sediments. J. Hazard. Mater. (2012) 215-216, 243-51.http://www.ncbi.nlm.nih.gov/pubmed/22421345

Nikodinovic-Runic, J., Casey, E., Duane, G.F., Mitic, D., Hume, A.R., Kenny, S.T., O'Connor, K.E. Process analysis of the conversion of styrene to biomass and medium chain length polyhydroxyalkanoate in a two-phase bioreactor. Biotechnol. Bioeng. (2011); 108, 2447-55. http://www.ncbi.nlm.nih.gov/pubmed/21520026