Naučni saradnik
Laboratorija za molekuarnu biologiju (LMB)

Institut za molekularnu genetiku i genetičko inženjerstvo (IMGGI),
Univerzitet u Beogradu,

V. Stepe 444a, 11010 Beograd, Srbija
Mob:   +381 64 4977 603
Tel:     +381 11 397 66 58
Fax:    +381 11 397 58 08
E-mail: djordjef@imgge.bg.ac.rs                                  

OBRAZOVANJE

2009 - Doktorirao na Freie Universität Berlin iz oblasti strukturne biologije, naslov teze:
“The Crystal Structure of Mj RelBE Protein Complex from Methanococcus jannaschii”
2000 - Diplomirao na Fakultetu za Fizičku hemiju, Univerzitet u Beogradu. Naslov diplomskog rada:
“Sinteza i karakterizacija kompozita Q-PbS-a i polistirena”

ISTRAŽIVAČKO ISKUSTVO

2009 - Naučni saradnik,LMB, IMGIE, Beograd, Srbija
2010 - 2011 - Gostujući naučnik na Freie Universität Berlin, Germany. Institute for Chemistry/Biochemistry and Crystallography (professor Saenger group) i Institute for Biochemistry (professor Erdmann group)
2005 - 2008 - AG Saenger , Institut für Chemie und Biochemie, FU Berlin, Nemačka
2007 - AG Saenger , Institut für Chemie und Biochemie, FU Berlin i AG Kroczek, Molecular Immunology, Robert Koch-Institute. Berlin, Nemačka
2001 – 2003 - AG Saenger , Institut für Chemie und Biochemie, FU Berlin. Berlin, Nemačka

OBLAST NAUČNOG INTERESOVANJA

Struktura i funkcija proteina kao, modelovanje proteinskih interackcija, studije uticaja mutacija na strukturu i funkciju proteina. Rendgenostrukturna analiza makromolekula i strukture visoke rezolucije malih molekula. Analiza eksperimentalne gustine naelektrisanja u tioureido jedinjenja. Markeri oksidativnog stresa i njihovo merenje.

ODABRANI NAUČNI RADOVI

Djordjevic, V., Kovac, M., Miljic, P., Murata, M., Takagi, A., Pruner, I., Francuski, D., Kojima, T., Radojkovic, D. A novel prothrombin mutation in two families with prominent thrombophilia - the first cases of antithrombin resistance in a Caucasian population (2013) Journal of Thrombosis and Haemostasis, 11 (10), pp. 1936-1939. http://www.ncbi.nlm.nih.gov/pubmed/23927452

Topic A, Francuski D, Markovic B, Stankovic M, Dobrivojevic S, Drca S, Radojkovic D. (2013) Gender-related reference intervals of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine determined by liquid chromatography-tandem mass spectrometry in Serbian population. Clin Biochem., 46(4-5):321-6. http://www.ncbi.nlm.nih.gov/pubmed/23261837

Narancic, T., Radivojevic, J., Jovanovic, P., Francuski, D., Bigovic, M., Maslak, V., Savic, V., Vasiljevic, B., O'Connor, K.E., Nikodinovic-Runic, J. (2013) Highly efficient Michael-type addition of acetaldehyde to β-nitrostyrenes by whole resting cells of Escherichia coli expressing 4-oxalocrotonate tautomerase Bioresource Technology, 142, pp. 462-46. http://www.ncbi.nlm.nih.gov/pubmed/23759430

Nikodinovic-Runic, J., Coulombel, L., Francuski, D., Sharma, N.D., Boyd, D.R., Ferrall, R.M.O., O'Connor, K.E. (2013) The oxidation of alkylaryl sulfides and benzo[b]thiophenes by Escherichia coli cells expressing wild-type and engineered styrene monooxygenase from Pseudomonas putida CA-3, Applied Microbiology and Biotechnology, 97 (11), pp. 4849-4858. http://www.ncbi.nlm.nih.gov/pubmed/22890778

Francuski B, Ivkovic B, Stojanovic I, Vladimirov S, Francuski D. 2-[2-(Trifluoromethyl)phenyl]-2H-1-benzopyran-4(3H)-one. Acta Crystallogr E. 2012; E68: 01522.

Jacimovic Z, Leovac V, Francuski D, Draskovic B, Bogdanovic G (2009) Crystal structure of dicholoro-(3,5-dimethyl-1H-pyrazole-1-carboxamidine-N,N')copper(II),Cu(C6H10N4)Cl2 Z Kristallogr NCS 224: 569-570.

Francuski D, Saenger W (2009) Crystal Structure of the Antitoxin–Toxin Protein Complex RelB–RelE from Methanococcus jannaschii J Mol Biol 393: 898-908. http://www.ncbi.nlm.nih.gov/pubmed/19712680

Alonso, J. C., Balsa, D., Cherny, I., Christensen, S. K., Espinosa, M., Francuski, D., et al. (2007). Bacterial Toxin-Antitoxin Systems as Targets for the Development of Novel Antibiotics. In R. A. Bonomo, & M. E. Tolmasky (Eds.), Enzyme-Mediated Resistance to Antibiotics: Mechanism, Dissemination, and Prospects for Inhibition (pp. 313-329). Washington, D.C.: ASM Press.