Naučni saradnik
Laboratorija za molekularnu biomedicinu

Institut za molekularnu genetiku i genetičko inženjerstvo (IMGGI),
Univerzitet u Beogradu,

V. Stepe 444a, 11010 Beograd, Srbija
Mob: +381 65 397 64 45
Tel:  +381 11 397 64 45
Fax: +381 11 397 58 08
E-mail: biljana.stankovic@imgge.bg.ac.rs                 

OBRAZOVANJE

2015 – doktor bioloških nauka, Biološki fakultet (BF), Univerzitet u Beogradu (UB), (naslov teze: "Molekularni markeri hronične inflamacije i apoptoze kod inflamatornih bolesti creva")
2009 – Diplomirani molekularni biolog i fiziolog, BF, UB

ISTRAŽIVAČKO ISKUSTVO

2016 – Naučni saradnik, Institut za molekularnu genetiku i genetičko inženjerstvo (IMGGI), UB
2011 – Istraživač saradnik, IMGGI, UB 
2010 – Istraživač pripravnik, IMGGI, UB

OBLAST NAUČNOG INTERESOVANJA

Istraživanje kojim se bavim usmereno je na identifikaciju molekularnih markera koji su asocirani sa hroničnim inflamatornim bolestima creva (HIBC), Kronovom bolešću (KB) i ulceroznim kolitisom (UK), kao i celijačnom bolešću (CB). Geni kandidati za ispitivanje rizika za nastanak HIBC su oni koji menjaju regulaciju procesa inflamacije i apoptoze, i na taj način utiču na nastanak hronične upale creva. Analiza genetičkih i ekspresionih profila pacijenata omogućiće bolje razumevanje patogeneze ovih bolesti i omogućiće pronalaženje novih markera HIBC. Jedan deo istraživanja usmeren je i na karakterizaciju farmakogenetičkih markera u terapiji KB i UK, kao i novih potencijalnih terapeutika. 

ODABRANI NAUČNI RADOVI

[1] Balasopoulou A, Stanković B, Panagiotara A, Nikčevic G, Peters BA, John A, Mendrinou E, Stratopoulos A, Legaki AI, Stathakopoulou V, Tsolia A, Govaris N, Govari S, Zagoriti Z, Poulas K, Kanariou M, Constantinidou N, Krini M, Spanou K, Radlovic N, Ali BR, Borg J, Drmanac R, Chrousos G, Pavlovic S, Roma E, Zukic B, Patrinos GP, Katsila T. Novel genetic risk variants for pediatric celiac disease. Hum Genomics. 2016 Oct 24; 10(1):34.

https://www.ncbi.nlm.nih.gov/pubmed/27836013 

[2] Stankovic B, Dragasevic S, Popovic D, Zukic B, Kotur N, Sokic-Milutinovic A, Alempijevic T, Lukic S, Milosavljevic T, Nikcevic G, Pavlovic S.  Variations in inflammatory genes as molecular markers for prediction of inflammatory bowel disease occurrence. J Dig Dis. 2015 Dec; 16(12):723-33.

https://www.ncbi.nlm.nih.gov/pubmed/26316104

[3]  Stanković B, Radlović N, Leković Z, Ristić D, Radlović V, Nikčević G, Kotur N, Vučićević K, Kostić T, Pavlović S, Zukic B. HLA genotyping in pediatric celiac disease patients. Bosn J Basic Med Sci. 2014 Aug 16; 14(3):171-6.

http://www.ncbi.nlm.nih.gov/pubmed/25172978

[4] Kotur N, Dokmanovic L, Janic D, Stankovic B, Krstovski N, Tosic N, Katsila T, Patrinos GP, Zukic B, Pavlovic S. TPMT gene expression is increased during maintenance therapy in childhood acute lymphoblastic leukemia patients in a TPMT gene promoter variable number of tandem repeat-dependent manner. Pharmacogenomics. 2015; 16(15):1701-12.

https://www.ncbi.nlm.nih.gov/pubmed/26411491

[5] Kotur N, Stankovic B, Kassela K, Georgitsi M, Vicha A, Leontari I, Dokmanovic L, Janic D, Krstovski N, Klaassen K, Radmilovic M, Stojiljkovic M, Nikcevic G, Simeonidis A, Sivolapenko G, Pavlovic S, Patrinos GP, Zukic B. 6-mercaptopurine influences TPMT gene transcription in a TPMT gene promoter variable number of tandem repeats-dependent manner. Pharmacogenomics. 2012; 13(3): 283-95.

https://www.ncbi.nlm.nih.gov/pubmed/22304581

[6] Klaassen K, Stankovic B, Kotur N, Djordjevic M, Zukic B, Nikcevic G, Ugrin M, Spasovski V, Srzentic S, Pavlovic S, Stojiljkovic M. New PAH gene promoter KLF1 and 3'-region C/EBPalpha motifs influence transcription in vitro. J Appl Genet. 2016 Jul 22.

https://www.ncbi.nlm.nih.gov/pubmed/27447460

[7] Obradović J, Djordjević N, Tošic N, Mrdjanović J, Stanković B, Stanić J, Zarić B, Perin B, Pavlović S, Jurišić V. Frequencies of EGFR single nucleotide polymorphisms in non-small cell lung cancer patients and healthy individuals in the Republic of Serbia: a preliminary study. Tumour Biol. 2016 Aug; 37(8):10479-86.

https://www.ncbi.nlm.nih.gov/pubmed/26846215

[8] Alimpic A, Kotur N, Stanković B, Marin P, Matevski V, Al Sheef N, Duletić-Laušević S. The in vitro antioxidative and cytotoxic effects of selected Salvia species water extracts. Journal Of Applied Botany And Food Quality 2015; 88(1).

[9] Radmilovic M, Zukic B, Petrovic MS, Bartsakoulia M, Stankovic B, Kotur N, Dokmanovic L, Georgitsi M, Patrinos GP, Pavlovic S. Functional analysis of a novel KLF1 gene promoter variation associated with hereditary persistence of fetal hemoglobin. Ann Hematol. 2013 Jan; 92(1):53-8.

https://www.ncbi.nlm.nih.gov/pubmed/23161389

 [10] Srzentić S, Spasovski V, Spasovski D, Zivković Z, Matanović D, Bascarević Z, Supić ZT, Stojiljković M, Karan-Djurasević T, Stanković B, Pavlović S, Nikcević G, Vukasinović Z. Association of gene variants in TLR4 and IL-6 genes with Perthes disease. Srp Arh Celok Lek. 2014 Jul-Aug; 142(7-8):450-6.

http://www.ncbi.nlm.nih.gov/pubmed/25233690

[11] Jančić I, Arsenović-Ranin N, Sefik-Bukilica M, Zivojinović S, Damjanov N, Spasovski V, Srzentić S, Stanković B, Pavlović S. -174G/C interleukin-6 gene promoter polymorphism predicts therapeutic response to etanercept in rheumatoid arthritis. Rheumatology International 2013; 33(6): 1481-6.

http://www.ncbi.nlm.nih.gov/pubmed/23233117

[12] Radmilovic M, Zukic B, Petrovic MS, Bartsakoulia M, Stankovic B, Kotur N, Dokmanovic L, Georgitsi M, Patrinos GP, Pavlovic S. Functional analysis of a novel KLF1 gene promoter variation associated with hereditary persistence of fetal hemoglobin. Annals of Hematology 2013; 92(1): 53-8.

http://www.ncbi.nlm.nih.gov/pubmed/23161389

[13] Radmilovic M, Zukic B, Stankovic B, Karan-Djurasevic T, Stojiljkovic M, Spasovski V, Tosic N, Dokmanovic L, Janic D, Pavlovic S. Thalassemia Syndromes in Serbia: An update. Hemoglobin 2010; 34 (5): 477-85.

http://www.ncbi.nlm.nih.gov/pubmed/20854122