Naučni saradnik
Laboratorija za molekularnu biologiju (LMB)

Institut za molekularnu genetiku i genetičko inženjerstvo (IMGGI),
Univerzitet u Beogradu (UB)

V. Stepe 444a, P. fah 23, 11010 Beograd, Srbija
Mob: +381 65 397 66 58
Tel:   +381 11 397 66 58
Fax:  +381 11 397 58 08
E-mail: aleksandradivac@imgge.bg.ac.rs

OBRAZOVANJE

2008 - Doktor bioloških nauka, Biološki fakultet (BF), UB, (Teza: „Promene strukture DNK izazvane proteinom HsOrc4“)
2003 - Magistar bioloških nauka, BF, UB
2001 - Diplomirani biolog, BF, UB

ISTRAŽIVAČKO ISKUSTVO

2008 -  naučni saradnik, IMGGI, UB
2002 - 2008 - istraživač saradnik, IMGGI, UB
2001 - 2002 - stipendista MNTRS

OSTALE AKTIVNOSTI

3. mesto na takmičenju Najbolja tehnološka inovacija Srbije (2008), predlog „Combined analysis of molecular markers CA19-9 i K-RAS G12 in diagnostics of pancreatic carcinoma“

Young Scientist Award na First Eastern European CF Conference:”What’s New in the Diagnosis, Treatment and Prevention of Cystic Fibrosis?”, (2008), Zagreb, Hrvatska

Nagrada za najbolji doktorski rad iz oblasti molekularne biologije (2008) Fondacije Goran Ljubijankić

OBLAST NAUČNOG INTERESOVANJA

Biomarkeri u bolestima čoveka, molekularna osnova plućnih i neuromišićnih bolesti, genetski faktori rizika u plućnim i kardiovaskularnim bolestima, razvoj metoda za neinvazivnu molekularnu dijagnostiku, analiza mutacija u genima: CFTR, alfa1-antitripsin i CARP/Ankrd1, funkcionalna karakterizacija proteina i njihovih mutiranih varijanti (alfa1-antitripsini  CARP/Ankrd1), zebrica (Danio rerio) kao model sistem za izučavanje bolesti čoveka, ekotoksikologija i genotoksikologija na model sistemu zebrice (Danio rerio)

ODABRANI NAUČNI RADOVI

Ljujic M, Divac Rankov A, Kojic S, Miranda E, Radojkovic D. (2014) Functional analysis of novel alpha-1 antitrypsin variants G320R and V321F. Mol Biol Rep, 41(9):6133-41. [PubMed]

Milosevic K, Nikolic A, Divac Rankov A, Ljujic M, Nestorovic B, Radojkovic D. (2013) Analysis of CFTR Gene Variants in Idiopathic Bronchiectasis in Serbian Children. Pediatr Allergy Immunol Pulmonol, 26(2):93-98. [PubMed]

Topic A, Stankovic M, Divac-Rankov A, Petrovic-Stanojevic N, Mitic-Milikic M, Nagorni-Obradovic L, Radojkovic D. (2012) Alpha-1-antitrypsin deficiency in Serbian adults with lung diseases. Genet Test Mol Biomarkers, 16(11):1282-6. [PubMed]

Kojic S, Nestorovic A, Rakicevic L, Belgrano A, Stankovic M, Divac A, Faulkner G.  (2010) A novel role for cardiac ankyrin repeat protein Ankrd1/CARP as a co-activator of the p53 tumor suppressor protein. Arch Biochem Biophys, 502(1):60-7. [PubMed]

Ljujic M, Topic A, Nikolic A, Divac A, Grujic M, Mitic-Milikic M, Radojkovic D (2010) Identification of a rare p.G320R alpha-1-antitrypsin variant in emphysema and lung cancer patients. Genet Mol Bio, 33(1): 5-8. [PubMed]

Divac A, Tomić B, Kušić J (2010) The role of adenosine triphosphate in the function of human origin recognition complex 4 protein. J Serb Chem Soc. 75(3): 317–22.

Kusic J, Tomic B, Divac A, Kojic S. (2010) Human initiation protein Orc4 prefers triple stranded DNA. Mol Biol Rep, 37(5):2317-22. [PubMed]

Radojkovic M, Ristic S, Divac A, Tomic B, Nestorovic A, Radojkovic D. (2009) Novel ORC4L gene mutation in B-cell lymphoproliferative disorders. Am J Med Sci, 338(6):527-9. [PubMed]

Stankovic M, Nikolic A, Divac A, Rakicevic L, Tomovic A, Mitic-Milikic M, Nagorni-Obradovic L, Grujic M, Petrovic-Stanojevic N, Andjelic-Jelic M, Dopudja-Pantic V, Radojkovic D. (2009) Matrix metalloproteinases gene variants in idiopathic disseminated bronchiectasis. J Investig Med, 57(3):500-3. [PubMed]

Stanković M, Nikolic A, Divac A, Tomovic A, Petrovic-Stanojevic N, Andjelic M, Dopudja-Pantic V, Surlan M, Vujicic I, Ponomarev D, Mitic-Milikic M, Kusic J, Radojkovic D. (2008) The CFTR M470V gene variant as a potential modifier of COPD severity – study of serbian population. Genet Test, 12(3):357-62. [PubMed]

Stefanovic D, Kusic J, Divac A, Tomic B. (2008) Formation of noncanonical DNA structures mediated by human ORC4, a protein component of origin recognition complex, Biochemistry, 47(33):8760-7. [PubMed]

Ljujic M, Topic A, Divac A, Nikolic A, Petrovic-Stanojevic N, Surlan M, Mitic-Milikic M, Radojkovic D. (2008) Isoelectric focusing phenotyping and denaturing gradient gel electrophoresis genotyping: a comparison of two methods in detection of alpha-1-antitrypsin variants, Transl Res, 151(5):255-9. [PubMed]

Ljujic M, Nikolic A, Divac A, Djordjevic V, Radojkovic D. (2006) Screening of alpha-1-antitrypsin gene by denaturing gradient gel electrophoresis (DGGE). J Biochem Biophys Methods, 68(3):167-73. [PubMed]

Divac A, Nikolic A, Mitic-Milikic M, Nagorni-Obradovic L, Petrovic-Stanojevic N, Dopudja-Pantic V, Nadaskic R, Savic A, Radojkovic D. (2005) CFTR mutations and polymorphisms in adults with disseminated bronchiectasis: a controversial issue. Thorax, 60(1):85. [PubMed]

Kusic J, Kojic S, Divac A, Stefanovic D. (2005) Noncanonical DNA elements in the lamin B2 origin of DNA replication. J Biol Chem, 280(11):9848-54. [PubMed]

Divac A, Nikolic A, Mitic-Milikic M, Nagorni-Obradovic L, Petrovic-Stanojevic N, Dopudja-Pantic V, Nadaskic R, Savic A, Radojkovic D. (2004) High frequency of the R75Q CFTR variation in patients with chronic obstructive pulmonary disease. J Cyst Fibros. 3(3):189-91. [PubMed]