Maja Gvozdenov

Research Assistant
Laboratory for molecular biology (LMB)

Institute of molecular genetics and genetic engineering (IMGGE),
University of Belgrade

V. Stepe 444a, P.Fah 23, 11010 Belgrade, Serbia
Mobile:           +381 64 397 66 58                          
Phone:           +381 11 397 66 58
Fax:               +381 11 397 58 08
E-mail: maja@imgge.bg.ac.rs

EDUCATION

2017 - PhD in Biology, Faculty of Biology (FB), University of Belgrade (UB): “Functional analysis of FIIc.1787G>A (prothrombin Belgrade) and FIIc.*64_*66del gene variants and their association with thrombophilia”
2012 - PhD student in Molecular biology, group for Molecular biology of Eukaryotes, Faculty of Biology, University of Belgrade
2012 - M.Sc.in Molecular Biology and Physiology (major: Experimental Biomedicine), Faculty of Biology, University of Belgrade
2010 - B.Sc. in Molecular Biology and Physiology, Faculty of Biology, University of Belgrade

RESEARCH EXPERIENCE

2014 - Research Assistant,LMB, IMGGE, University of Belgrade
2013 - 2014 - Research Trainee, LMB, IMGGE, University of Belgrade
2012 - 2013 - Volunteer, LMB, IMGGE, University of Belgrade
2011 - 2012 - Master student in Laboratory for Cardiovascular Physiology, Institute for Medical Research, University of Belgrade

RESEARCH INTEREST

  • prothrombin 3'end processing and regulation of prothrombin gene expression
  • role of micro RNA in prothrombin gene expression
  • functional analysis of 3'end prothrombin gene variants
  • 3'end of prothrombin gene  in etiology of thrombophilia, cancer and inflammation
  • screening for new thrombophilia markers
  • inherited thrombophilia

SELECTED PUBLICATIONS

  1. Miljic P, Gvozdenov M, Takagi Y, Takagi A, Pruner I, Dragojevic M, Tomic B, Bodrozic J, Kojima T, Radojkovic D, Djordjevic V.Clinical and biochemical characterization of the prothrombin Belgrade mutation in a large Serbian pedigree: new insights into the antithrombin resistance mechanism. J Thromb Haemost. 2017;15(4):670-7.
  2. Mitrovic M, Suvajdzic N, Elezovic I, Bogdanovic A, Djordjevic V, Miljic P,  Djunic I,  Gvozdenov M, Colovic N, Virijevic M, Lekovic D, Vidovic A, Tomin D. Thrombotic events in acute promyelocytic leukemia. Thromb Res. 2015; 135(4):588-93.
  3. Djordjevic V, Gvozdenov  M, Pruner I, Kovac  M,  Tomic B, Stankovic M, Radojkovic D.The prevalence of the PAI-1 4G/5G polymorphism in women with fetal loss – first data for Serbian population. J Med Bioch. 2014;33(2):203-8.
  4. Pruner I, Djordjevic V, Gvozdenov M,Tomic B, Radojkovic D. Determination of transgene copy number in stably transfected mammalian cells by PCR-capillary electrophoresis assay. Biochem Genet. 2014;52(3-4):159-65.
  5. Djordjevic V, Pruner I, Tomic B, Nestorovic A, Gvozdenov M, Kovac M, Radojkovic D. The 3' End Prothrombin Gene Variants in Patients With Different Thrombotic Events. Lab Med. 2014;45:309-14.
  6. Gvozdenov M, Pruner I, Tomic B, Aradjanski M, Antonijevic N, Radojkovic D, Djordjevic V. Prothrombin 3’ end gene variants in isolated pulmonary embolism-the first report of  FIIc.*64_*66del and FIIc.*303T˃C variants. Acta Cardiol. 2015; 70(2):177-82.
  7. Aradjanski M, Djordjevic V, Pruner I, Tomic B, Gvozdenov M, Kovac M, Radojkovic  D. The 3' end prothrombin gene variants in Serbian patients with idiopathic thrombophilia. BJMG. 2015; 17(2):43-8.
  8. Gvozdenov M, Pruner I, Tomic B, Kovac M, Radojkovic D, Djordjevic V. The effect of FII c.1787G>A (prothrombin Belgrade) mutation on prothrombin gene expression in vitro. Mol Biol. 2017; 51(1):49–52.

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