Research Associate

Institute of molecular genetics and genetic engineering (IMGGE),
University of Belgrade

V. Stepe 444a, P.Fah 23, 11010 Belgrade, Serbia
Mobile: +381 65 397 62 12                          
Phone:  +381 11 397 62 12
Fax:     +381 11 397 58 08
E-mail: danijeladrakulic@imgge.bg.ac.rs

EDUCATION

2011 - PhD in Biological Sciences, Faculty of Biology (FB), UB (Analysis of effects of SOX2 overexpression on pluripotency, proliferation and neural differentation of embryonal carcinoma NT2/D1 cells)

2005 - M.Sc. in Biology, FB, UB

2000 - B.Sc. in Molecular biology and physiology, FB, University of Belgrade

RESEARCH EXPERIENCE

2012 - Research Associate, Laboratory for Human Molecular Genetics (LHMG), IMGGE

2005 - 2012 - Research Assistant, LHMG, IMGGE

2002 - 2005 - Research Trainee, LHMG, IMGGE

CAREER HISTORY

2013 - WP leader (WP3 Reinforcement of human resources) of projectFP7-REGPOT-2012-2013-1 “Strengthening the Research Potential of IMGGE through Reinforcement of Biomedical Science of Rare Diseases in Serbia – en route for innovation”- SERBORDISinn

2012 - Lecturer on Faculty of Biology, University of Belgrade on Doctoral degree program (Methodology in Molecular Biology)

2009 - Wellcome Trust Advanced Course: Genetic Manipulation ofES cells, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom, 20 October- 8 November

2007 - Preimplantation Genetic Diagnosis Workshop, UCL centre, London,United Kingdom, 16-20 April

2004 - University of Nottingham, Queen’s Medical Centre, Nottingham, United Kingdom, September 2004.- learning technique RNA-RNA in situ hybridization

2003 - Theoretical and Practical Course: Molecular Cytogenetics using fluorescent in situhybridisation techniques, Sfax, Тunisia, 4-12 April

RESEARCH INTEREST

Analysis the effects of modulation of SOXB1 expression on pluripotency, proliferation, migration, neural differentiation and cell death of embryonal carcinoma and cancer cell lines

Introducing and application of fluorescent in situ hybridization (FISH) for detection of numerical and structural chromosome aberrations in humans

SELECTED PUBLICATIONS

Drakulic D, Marjanovic Vicentic J, Schwirtlich M, Tosic J, Krstic A, Klajn A, Stevanovic M. The overexpression of SOX2 affects the migration of humanteratocarcinoma cell line NT2/D1. An. Acad. Bras. Ciênc., in press

Klajn A, Drakulic D, Tosic M, Pavkovic Z, Schwirtlich M, Stevanovic M. Effects of constitutive SOX2 overexpression on neural differentiation of NT2/D1 cells. Biochemistry (Moscow), in press

Cuturilo G, Drakulic D, Krstic A, Gradinac M, Ilisic T, Parezanovic V, Milivojevic M, Stevanovic M, Jovanovic I. The role of modern imaging techniques in the diagnosis of malposition of the branch pulmonary arteries and possible association with microdeletion 22q11.2. Cardiol Young. 2013 23(2):181-8. http://www.ncbi.nlm.nih.gov/pubmed/22717372

Drakulic D, Krstic A, Stevanovic M. Establishment and initial characterization of SOX2-overexpressing NT2/D1 cell clones. Genet Mol Res. 2012 11(2):1385-400.  http://www.ncbi.nlm.nih.gov/pubmed/22653585

Cuturilo G, Menten B, Krstic A, Drakulic D, Jovanovic I, Parezanovic V, Stevanovic M. 4q34.1-q35.2 deletion in a boy with phenotype resembling 22q11.2 deletion syndrome. Eur J Pediatr. 2011 170(11):1465-70. http://www.ncbi.nlm.nih.gov/pubmed/21833498

Djordjević VA, Jovanović JV, Pavković-Lučić SB, Drakulić DD, Djurović MM, Gotić MD. Cytogenetic findings in Serbian patients with Turner's syndrome stigmata. Genet Mol Res. 2010 9(4):2213-21. http://www.ncbi.nlm.nih.gov/pubmed/21064029

Jovicić D, Milacić S, Vukov TD, Rakić B, Stevanović M, Drakulić D, Rakić R, Bukvić N. Detection of premature segregation of centromeres in persons exposed to ionizing radiation. Health Phys. 2010 98(5):717-27.

http://www.ncbi.nlm.nih.gov/pubmed/20386201

Milivojević M, Nikčević G, Kovačević-Grujičić N, Krstić A, Mojsin M, Drakulić D, Stevanović M. Involvement of ubiquitous and TALE transcription factors, as well as liganded RXR in the regulation of human SOX2 gene expression in NT2/D1 embryonal carcinoma cell line. Archives of Biological Science. 2010 62:199-210.

Djordjević V, Dencić-Fekete M, Jovanović J, Drakulić D, Stevanović M, Janković G, Gotić M. Pattern of trisomy 1q in hematological malignancies: a single institution experience. Cancer Genet Cytogenet. 2008 186(1):12-8.

http://www.ncbi.nlm.nih.gov/pubmed/18786437

Cuturilo G, Drakulic D, Stevanovic M, Jovanovic I, Djukic M, Miletic-Grkovic S, Atanaskovic-Markovic M. A rare association of interrupted aortic arch type C and microdeletion 22q11.2. Eur J Pediatr. 2008 167(10):1195-8.

http://www.ncbi.nlm.nih.gov/pubmed/18040716

Drakulić D, Nikčević G, Djordjević V, Stevanović M. Generation of a whole chromosome painting probe from monochromosomal hybrid cells by the Alu-polymerase chain reaction. Archives of Biological Science. 2007 59:89-95.

Mojsin M, Djurovic J, Petrovic I, Krstic A, Drakulic D, Savic T, Stevanovic M. Rapid detection and purification of sequence specific DNA binding proteins using magnetic separation. Journal of the Serbian Chemical Society. 2006 71:135-141.

Miljkovic Dj, Samardzic T, Drakulic D, Stosic-Grujicic S, Trajkovic V. Immunosuppressants leflunomide and mycophenolic acid inhibit fibroblast IL-6 production by distinct mechanisms. Cytokine. 2002 19(4):181-6. http://www.ncbi.nlm.nih.gov/pubmed/12297111