Aleksandra Divac Rankov

Research Associate
Laboratory for Molecular Biology (LMB)

Institute of Molecular Genetics and Genetic Engineering (IMGGE),
University of Belgrade (UB)

V. Stepe 444a, PO box 23, 11010 Belgrade, Serbia
Mobile:           +381 65 397 66 58                          
Phone:           +381 11 397 66 58
Fax:               +381 11 397 58 08
E-mail: aleksandradivac@imgge.bg.ac.rs

EDUCATION

2008 - PhD in Biology, Faculty of Biology (FB), UB (Thesis: “Structural changes of DNA mediated by protein HsORC4”)

2003 - M.Sc. in Biology, FB, UB

2001 - B.Sc. in Biology, FB, UB

RESEARCH EXPERIENCE

2008 - Research Associate Laboratory for Molecular Biology (LMB) , IMGGE

2002 - 2008 - Research Assistant LMB, IMGGE

2001 - 2002 - Research Trainee, LMB, IMGGE

RESEARCH INTEREST

Human disease biomarkers, molecular basis of lung and neuromuscular diseases, genetic risk factors for lung diseasees, non-invasive molecular diagnostics, mutation analysis in CFTR, alpha-1 antitrypsin (A1AT) and CARP/Ankrd1 genes, functional characterization of proteins (wild-type and mutated variants of A1AT and CARP/Ankrd1 genes), zebrafish (Danio rerio) as a model system for human diseases, zebrafish (Danio rerio) in ecotoxicology and genotoxycology research

SELECTED PUBLICATIONS

  1. Ljujic M, Divac Rankov A, Kojic S, Miranda E, Radojkovic D. (2014) Functional analysis of novel alpha-1 antitrypsin variants G320R and V321F. Mol Biol Rep, 41(9):6133-41. [PubMed]
  2. Milosevic K, Nikolic A, Divac Rankov A, Ljujic M, Nestorovic B, Radojkovic D. (2013) Analysis of CFTR Gene Variants in Idiopathic Bronchiectasis in Serbian Children. Pediatr Allergy Immunol Pulmonol, 26(2):93-98. [PubMed]
  3. Topic A, Stankovic M, Divac-Rankov A, Petrovic-Stanojevic N, Mitic-Milikic M, Nagorni-Obradovic L, Radojkovic D. (2012) Alpha-1-antitrypsin deficiency in Serbian adults with lung diseases. Genet Test Mol Biomarkers, 16(11):1282-6. [PubMed]
  4. Kojic S, Nestorovic A, Rakicevic L, Belgrano A, Stankovic M, Divac A, Faulkner G.  (2010) A novel role for cardiac ankyrin repeat protein Ankrd1/CARP as a co-activator of the p53 tumor suppressor protein. Arch Biochem Biophys, 502(1):60-7. [PubMed]
  5. Ljujic M, Topic A, Nikolic A, Divac A, Grujic M, Mitic-Milikic M, Radojkovic D (2010) Identification of a rare p.G320R alpha-1-antitrypsin variant in emphysema and lung cancer patients. Genet Mol Bio, 33(1): 5-8. [PubMed]
  6. Divac A, Tomić B, Kušić J (2010) The role of adenosine triphosphate in the function of human origin recognition complex 4 protein. J Serb Chem Soc. 75(3): 317–22.
  7. Kusic J, Tomic B, Divac A, Kojic S. (2010) Human initiation protein Orc4 prefers triple stranded DNA. Mol Biol Rep, 37(5):2317-22. [PubMed]
  8. Radojkovic M, Ristic S, Divac A, Tomic B, Nestorovic A, Radojkovic D. (2009) Novel ORC4L gene mutation in B-cell lymphoproliferative disorders. Am J Med Sci, 338(6):527-9. [PubMed]
  9. Stankovic M, Nikolic A, Divac A, Rakicevic L, Tomovic A, Mitic-Milikic M, Nagorni-Obradovic L, Grujic M, Petrovic-Stanojevic N, Andjelic-Jelic M, Dopudja-Pantic V, Radojkovic D. (2009) Matrix metalloproteinases gene variants in idiopathic disseminated bronchiectasis. J Investig Med, 57(3):500-3. [PubMed]
  10. Stanković M, Nikolic A, Divac A, Tomovic A, Petrovic-Stanojevic N, Andjelic M, Dopudja-Pantic V, Surlan M, Vujicic I, Ponomarev D, Mitic-Milikic M, Kusic J, Radojkovic D. (2008) The CFTR M470V gene variant as a potential modifier of COPD severity – study of serbian population. Genet Test, 12(3):357-62. [PubMed]
  11. Stefanovic D, Kusic J, Divac A, Tomic B. (2008) Formation of noncanonical DNA structures mediated by human ORC4, a protein component of origin recognition complex, Biochemistry, 47(33):8760-7. [PubMed]
  12. Ljujic M, Topic A, Divac A, Nikolic A, Petrovic-Stanojevic N, Surlan M, Mitic-Milikic M, Radojkovic D. (2008) Isoelectric focusing phenotyping and denaturing gradient gel electrophoresis genotyping: a comparison of two methods in detection of alpha-1-antitrypsin variants, Transl Res, 151(5):255-9. [PubMed]
  13. Ljujic M, Nikolic A, Divac A, Djordjevic V, Radojkovic D. (2006) Screening of alpha-1-antitrypsin gene by denaturing gradient gel electrophoresis (DGGE). J Biochem Biophys Methods, 68(3):167-73. [PubMed]
  14. Divac A, Nikolic A, Mitic-Milikic M, Nagorni-Obradovic L, Petrovic-Stanojevic N, Dopudja-Pantic V, Nadaskic R, Savic A, Radojkovic D. (2005) CFTR mutations and polymorphisms in adults with disseminated bronchiectasis: a controversial issue. Thorax, 60(1):85. [PubMed]
  15. Kusic J, Kojic S, Divac A, Stefanovic D. (2005) Noncanonical DNA elements in the lamin B2 origin of DNA replication. J Biol Chem, 280(11):9848-54. [PubMed]
  16. Divac A, Nikolic A, Mitic-Milikic M, Nagorni-Obradovic L, Petrovic-Stanojevic N, Dopudja-Pantic V, Nadaskic R, Savic A, Radojkovic D. (2004) High frequency of the R75Q CFTR variation in patients with chronic obstructive pulmonary disease. J Cyst Fibros. 3(3):189-91. [PubMed]

 

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