Principal Research Fellow
Institute of molecular genetics and genetic engineering (IMGGE)

University of Belgrade
V. Stepe 444a, P.Fah 23, 11010 Belgrade, Serbia

Mobile:           +381 65 397 64 14              
Phone:           +381 11 397 64 14
Fax:               +381 11 397 58 08
E-mail: mdkojic@imgge.bg.ac.rs

EDUCATION

1994 - PhD in Molecular Genetics and Genetic Engineering, Faculty of Biology (FB), UB (ANALYSIS OF REGULATORY REGIONS AND EXPRESSION OF THE sgm GENE FROM Micromospora zionensis))

1992 - M.Sc. in Molecular Genetics and Genetic Engineering, FB, UB

1987 - B.Sc. in Biology, FB, University of Belgrade

RESEARCH EXPERIENCE

2012 - Present Principal Research Fellow Laboratory for Plant Molecular Biology, IMGGE

2007 - 2013 - Assistant Research Professor in Microbiology, Department of Microbiology     and Immunology, Cornell University Weill Medical College

2003-2007 - Instructor in Microbiology, Department of Microbiology and Immunology, Cornell University Weill Medical College

1997-2003 - Postdoctoral Fellow in Microbiology, Cornell University Medical College

1994-1997 - Research Associate LMGIM,IMGGE

1992-1994 - Research Assistant LMGIM, IMGGE

1988 -1992 - Research Trainee, LMGIM, IMGGE

RESEARCH INTEREST

Molecular genetics, development of new selectable markers and shuttle vectors, maintenance of genomic integrity, DNA-repair, homologous recombination, resolution of recombinational intermediates, meiosis, cell cycle, cellular defense against oxidative insult.   

SELECTED PUBLICATIONS

20)Bautista-España D, Anastacio-Marcelino E, Horta-Valerdi G, Celestino-Montes A, Kojic M, Negrete-Abascal E, Reyes-Cervantes H, Vázquez-Cruz C, Guzmán P, Sánchez-Alonso P. The Telomerase Reverse Transcriptase Subunit from the Dimorphic Fungus Ustilago maydis. PLoS One. 2014 Oct 9;9(10):e109981. doi: 10.1371/journal.pone.0109981. eCollection 2014.  http://www.ncbi.nlm.nih.gov/pubmed/25299159

19)Kojic M, Sutherland JH, Pérez-Martín J, Holloman WK. Initiation of Meiotic Recombination in Ustilago maydis. Genetics. 2013 Dec;195(4):1231-40. doi: 10.1534/genetics.113.156752. Epub 2013 Sep 27.

http://www.ncbi.nlm.nih.gov/pubmed/24077302

18) Yu EY, Kojic M, Holloman WK, Lue NF. Brh2 and Rad51 promote telomere maintenance in Ustilago maydis, a new model system of DNA repair proteins at telomeres. DNA Repair (Amst). 2013 Jul; 12(7):472-9. doi: 10.1016/j.dnarep.2013.04.027. Epub 2013 May 28.http://www.ncbi.nlm.nih.gov/pubmed/23726221

17) Zhou Q, Kojic M, Holloman WK. Dss1 Release Activates DNA Binding Potential in Brh2. Biochemistry. 2012 Nov 13; 51(45):9137-46. doi: 10.1021/bi3011187. Epub 2012 Nov 2. http://www.ncbi.nlm.nih.gov/pubmed/23094644

16) Kojic M, Holloman WK. Brh2 domain function distinguished by differential cellular responses to DNA damage and replication stress. Mol Microbiol. 2012 Jan; 83(2): 351-61. doi: 10.1111/j.1365-2958.2011.07935.x. Epub 2011 Dec 15. http://www.ncbi.nlm.nih.gov/pubmed/22171788

15)Kojic M, Zhou Q, Fan J, Holloman WK. Mutational analysis of Brh2 reveals requirements for compensating mediator functions. Mol Microbiol. 2011 Jan;79(1):180-91. doi: 10.1111/j.1365-2958.2010.07440.x. Epub 2010 Nov 2.http://www.ncbi.nlm.nih.gov/pubmed/21166902

14) Zhou Q, Mazloum N, Mao N, Kojic M, Holloman WK. Dss1 regulates interaction of Brh2 with DNA.Biochemistry. 2009 Dec 22; 48(50):11929-38. http://www.ncbi.nlm.nih.gov/pubmed/19919104

13) Mao N, Kojic M, Holloman WK. Role of Blm and collaborating factors in recombination and survival following replication stress in Ustilago maydis. DNA Repair (Amst). 2009 Jun 4;8(6): 752-9. Epub 2009 Apr 5. http://www.ncbi.nlm.nih.gov/pubmed/19349216

12) Zhou Q, Kojic M, Holloman WK. DNA-binding Domain within the Brh2 N Terminus is the Primary Interaction Site for Association with DNA.J Biol Chem. 2009 Mar 27; 284(13):8265-73. Epub 2009 Feb 1. http://www.ncbi.nlm.nih.gov/pubmed/19182269

11) Kojic M, Mao N, Zhou Q, Lisby M, Holloman WK.Compensatory role for Rad52 during recombinational repair in Ustilago maydis. Mol Microbiol. 2008 Feb 3;67(5):1156-1168. Epub 2008 Jan 15 http://www.ncbi.nlm.nih.gov/pubmed/18208529.

10) Mao N, Zhou Q, Kojic M, Perez-Martin J, Holloman WK. Ortholog of BRCA2-interacting protein BCCIP controls morphogenetic responses during DNA replication stress in Ustilago maydis. DNA Repair (Amst). 2007 Nov; 6(11):1651-60. Epub 2007 Jul 12. http://www.ncbi.nlm.nih.gov/pubmed/17627904

9) Zhou Q, Kojic M, Cao Z, Lisby M, Mazloum NA, Holloman WK. Dss1 interaction with Brh2 as a regulatory mechanism for recombinational repair. Mol Cell Biol. 2007 Apr; 27(7):2512-26. Epub 2007 Jan 29. http://www.ncbi.nlm.nih.gov/pubmed/17261595

8) Kojic M, Zhou Q, Lisby M, Holloman WK. Rec2 Interplay with both Brh2 and Rad51 Balances Recombinational Repair in Ustilago maydis. Mol Cell Biol. 2006 Jan;26(2):678-88. http://www.ncbi.nlm.nih.gov/pubmed/16382157

7) Kojic M, Zhou Q, Lisby M, Holloman WK. Brh2-Dss1 Interplay Enables Properly Controlled Recombination in Ustilago maydis. Mol Cell Biol. 2005 Apr;25(7):2547-57. http://www.ncbi.nlm.nih.gov/pubmed/15767662

6) Kojic M, Holloman WK. BRCA2-RAD51-DSS1 Interplay Examined from a Microbial Perspective. Cell Cycle. 2004 Mar; 3(3):247-248. http://www.ncbi.nlm.nih.gov/pubmed/14726651

5) Kojic M, Yang HJ, Kostrub CF, Pavletich NP, Holloman WK. The BRCA2    interacting protein DSS1 is vital for DNA repair, recombination, and genome stability in Ustilago maydis. MOLECULAR CELL 12 (4): 1043-1049 OCT 2003. http://www.ncbi.nlm.nih.gov/pubmed/14580353

4) Kojic, M.,  Corwin F. Kostrub, Andrew R. Buchman, and William K. Holloman (2002) BRCA2 Homolog Required for Proficiency in DNA Repair, Recombination, and Genome Stability in Ustilago maydis . Molecular Cell, Vol. 10, 683–691. http://www.ncbi.nlm.nih.gov/pubmed/12408834

3) Kojic, M., Thompson, C. W. and Holloman, W. K. (2001) Disruptions of the Ustilago maydis REC2 gene identify a protein domain important in directing recombinational repair of DNA.  Mol. Microbiol. 40 (6), 1415-1426. http://www.ncbi.nlm.nih.gov/pubmed/11442839

2) Kojic, M. and Holloman, W.K. (2000) Shuttle vectors for genetic manipulations in Ustilago maydis. Can. J. Microbiol. 46, 333-338. http://www.ncbi.nlm.nih.gov/pubmed/10779869 

1) Kojic, M., Milojevic, N., Vasiljevic, B. (1999) Gentamicin-resistance determinants confer background-dependent hygromycin B resistance. Microbial Drug Resistance, 5, 177-182. http://www.ncbi.nlm.nih.gov/pubmed/10566866