Research Associate
Laboratory for Human Molecular Genetics

Institute of Molecular Genetics and Genetic Engineering (IMGGE),
University of Belgrade

V. Stepe 444a, P.Box 23, 11010 Belgrade, Serbia
Mobile:   +381 65  3976212                           
Phone:   +381 11 3976212
Fax:       +381 11 397 58 08


2009 - PhD in Biological Sciences, Faculty of Biology (FB), UB (“Characterization of the basal promoter of the human SOX3 gene and identification of the regulatory elements responsible for the SOX3 gene induction by retinoic acid“)

2000 - M.Sc. in Biological Sciences, FB, UB

1996 - B.Sc. in Molecular Biology and Physiology, FB, University of Belgrade


2010 -  Research Associate, Laboratory for Human Molecular Genetics (LHMG), IMGGE

2001 - 2010 - Research Assistant, LHMG, IMGGE

1998 - 2001 - Research Trainee, Laboratory for Molecular Hematology (LMH), IMGGE


2014 - member of the Ethical Commitee of the IMGGE, UB

2011 - WP Leader “Molecular genetic analysis of populations that resided in southwestern Serbia from Bronze Age to Middle Ages“ of the project “Ethnogenesis of the Serbs during the Middle Ages (until c.1250): a comparative analysis of the historic-cultural heritage, genetic material and artefacts ofmaterial culture from the aspect of analytical chemistry“ (MESTDS, 47025, 2011-2014)

2001 - Laboratory for Human Molecular Genetics, IMGGE

1998 - 2001 - Laboratory for Molecular Hematology, IMGGE


  • Research of the contemporary Serbian population diversity based on mitochondrial DNA variability which represents a foundation for further comparative analysis of ancient populations that inhabited region of Serbia
  • Testing the bioactive components from edible mushrooms and analysis of their therapeutic potential by applying in vitro tests for cytotoxity, cell adhesion and cell migratory capacity. Analysis of the effect of bioactive compounds on modulation of expression of selected SOX genes and well-known tumor suppressors and oncogenes.


Kovacevic-Grujicic N, Mojsin M, Popovic J, Petrovic I, Topalovic V, Stevanovic M. Cyclic AMP response element binding (CREB) protein acts as a positive regulator of SOX3 gene expression in NT2/D1 cells. BMB Rep. 2014 Apr;47(4):197-202.

Milivojevic M, Petrovic I, Kovacevic-Grujicic N, Popovic J, Mojsin M, Stevanovic M. Construction and functional analysis of novel dominant-negative mutant of human SOX18 protein. Biochemistry (Mosc). 2013 Nov;78(11):1287-92. doi: 10.1134/S0006297913110096.

Mojsin M, Popovic J, Kovacevic Grujicic N, Stevanovic M. TG-interacting factor (TGIF) downregulates SOX3 gene expression in the NT2/D1 cell line. J Genet Genomics. 2012 Jan;39(1):19-27. doi: 10.1016/j.jgg.2011.11.006. Epub 2011 Dec 24.

Nikčević G, Kovačević-Grujičić N, Mojsin M, Krstić A, Savić T, Stevanović M. Regulation of the SOX3 gene expression by retinoid receptors. Physiol Res. 2011;60 Suppl 1:S83-91. Epub 2011 Jul 19. Review.

Petrovic I, Kovacevic-Grujicic N, Stevanovic M Early growth response protein 1 acts as an activator of SOX18 promoter. Exp Mol Med. 2010 Feb 28;42(2):132-42. doi: 10.3858/emm.2010.42.2.015.

Mojsin M, Kovacevic-Grujicic N, Krstic A, Popovic J, Milivojevic M, Stevanovic M. Comparative analysis of SOX3 protein orthologs: Expansion of homopolymeric amino acid tracts during vertebrate evolution. Biochem Genet. 2010 Aug;48(7-8):612-23. doi: 10.1007/s10528-010-9343-2. Epub 2010 May 21.

Petrovic I, Kovacevic-Grujicic N, Stevanovic M. ZBP-89 and Sp3 down-regulate while NF-Y up-regulates SOX18 promoter activity in HeLa cells. Mol Biol Rep. 2009 May;36(5):993-1000. doi: 10.1007/s11033-008-9272-x. Epub 2008 May 22.

Nikcević G, Savić T, Kovacević-Grujicić N, Stevanović M. Up-regulation of the SOX3 gene expression by retinoic acid: characterization of the novel promoter-response element and the retinoid receptors involved. J Neurochem. 2008 Dec;107(5):1206-15. doi: 10.1111/j.1471-4159.2008.05670.x. Epub 2008 Sep 11.

Kovacevic-Grujicic N, Mojsin M, Djurovic J, Petrovic I, Stevanovic M. Comparison of promoter regions of SOX3, SOX14 and SOX18 orthologs in mammals. DNA Seq. 2008 Jun;19(3):185-94.

Mojsin M, Grujicić NK, Nikcević G, Krstić A, Savić T, Stevanović M. Mapping of the RXRalpha binding elements involved in retinoic acid induced transcriptional activation of the human SOX3 gene. Neurosci Res. 2006 Dec;56(4):409-18. Epub 2006 Sep 26.

Kovacevic Grujicic N, Mojsin M, Krstic A, Stevanovic M. Functional characterization of the human SOX3 promoter: identification of transcription factors implicated in basal promoter activity. Gene. 2005 Jan 3;344:287-97. Epub 2004 Dec 10.

Nikcevic G, Kovacevic-Grujicic N, Stevanovic M. Improved transfection efficiency of cultured human cells. Cell Biol Int. 2003;27(9):735-7.

Skoko N, Argamante B, Grujicić NK, Tisminetzky SG, Glisin V, Ljubijankić G. Expression and characterization of human interferon-beta1 in the methylotrophic yeast Pichia pastoris. Biotechnol Appl Biochem. 2003 Dec;38(Pt 3):257-65.

The rat bbminy-globin promoter: nuclear protein factors and erythroid-specific induction of transcription. Pavlović S, Mitrović T, Nikcević G, Grujicić N, Lazić D, Glisin V, Popović Z. Cell Mol Life Sci. 1999 Nov 30;56(9-10):871-81.